GeneTex
  • Country / Location Selection

United States (US)
Histone Modifications

Histone Modifications

Histone-Modification

The nucleosome core particle is the fundamental structural unit of the eukaryotic genome. It consists of a histone octamer composed of two H2A-H2B dimers and a H3-H4 tetramer wrapped by ~146 base pairs of DNA. A linker histone (i.e., H1) associates with the nucleosomal dyad as well as with linker DNA on either side of the nucleosome, resulting in the formation of the chromatosome. All the core and linker histones are post-translationally decorated, with at least 160 total modifications such as acetylation, methylation, and phosphorylation. These modifications are thought to impact chromatin functions by either altering chromatin packaging or through the recruitment/inhibition of specific chromatin binding factors. Please see below for highlighted antibodies or click the button to find all related products.

See all related Products

 

Highlighted Products
    
Histone H2A.XS139ph (phospho Ser139) antibody (GTX127340)

Histone H2A.XS139ph (phospho Ser139) antibody (GTX127340)

Histone H3K27me3 (Tri-methyl Lys27) antibody (GTX121184)

Histone H3K27me3 (Tri-methyl Lys27) antibody
(GTX121184)

 
SMYD3 antibody (GTX121945)

SMYD3 antibody
(GTX121945)

 

 

Newsletter
GeneTex Supports YCharOS in Revolutionizing Antibody Validation

GeneTex Supports YCharOS in Revolutionizing Antibody Validation

Newsletter
Article Alert: Induced Proteasomal Degradation of TET2 Leads to EGFR-Tyrosine Kinase Inhibitor Resistance In Non-Small Cell Lung Cancer

Induced Proteasomal Degradation of TET2 Leads to EGFR-Tyrosine Kinase Inhibitor Resistance In NSCLC

Article Alert: Induced Proteasomal Degradation of TET2 Leads to EGFR-Tyrosine Kinase Inhibitor Resistance In Non-Small Cell Lung Cancer
Literature

Flyer - IVD-related Products

Download the latest version of GeneTex's IVD-related Products flyer.
Literature

Flyer - Cited Antibodies 2024 Q2

Download the latest version of GeneTex's Antibodies for Cited Antibodies 2024 Q2 flyer.
Articles

IVD-related Products and Services

Newsletter
Article Alert: Urothelial Epigenome Reprogramming by Uropathogenic E. coli Underlies Recurrent Urinary Tract Infection Susceptibility

Urothelial Epigenome Reprogramming by Uropathogenic E. coli Underlies Recurrent UTI Susceptibility

Article Alert: Urothelial Epigenome Reprogramming by Uropathogenic E. coli Underlies Recurrent Urinary Tract Infection Susceptibility
Newsletter

Lateral Flow Assay for Influenza & SARS-CoV-2 Viruses Detection

Influenza A & B Virus Antibodies (IVD grade)
Literature
Brochure - Cited Antibodies

Brochure - Cited Antibodies

Download the latest version of GeneTex's Cited Antibodies brochure.
Literature
Cited Antibodies

Flyer - Cited Antibodies

Download the latest version of GeneTex's cited antibodies flyer.
Literature
World Class Validated Antibodies

Brochure - World Class Validated Antibodies

Download the latest version of GeneTex's World Class Validated Antibodies brochure.
Literature
Epigenetics poster

Poster - Epigenetics

Download the latest version of GeneTex's Epigenetics poster
Literature

Flyer - Epigenetics Histone Modification

Download the latest version of GeneTex's epigenetics histone modification flyer.
Literature

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.
Literature

Flyer - IVD-related Products

Download the latest version of GeneTex's IVD-related Products flyer.
Literature

Flyer - Cited Antibodies 2024 Q2

Download the latest version of GeneTex's Antibodies for Cited Antibodies 2024 Q2 flyer.
Literature
Brochure - Cited Antibodies

Brochure - Cited Antibodies

Download the latest version of GeneTex's Cited Antibodies brochure.
Literature
Cited Antibodies

Flyer - Cited Antibodies

Download the latest version of GeneTex's cited antibodies flyer.
Literature
World Class Validated Antibodies

Brochure - World Class Validated Antibodies

Download the latest version of GeneTex's World Class Validated Antibodies brochure.
Literature
Epigenetics poster

Poster - Epigenetics

Download the latest version of GeneTex's Epigenetics poster
Literature

Flyer - Epigenetics Histone Modification

Download the latest version of GeneTex's epigenetics histone modification flyer.
Literature

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.