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Summary Binding specificity was confirmed in peptide inhibition studies with the intact protein. The antibody does not recognize the native estrogen receptor in the inactive 8S oligomeric state, but reacts efficiently with the activated 4S receptor. In immunoprecipitation studies, this antibody has been shown to only IP the active receptor.

Summary This antibody recognizes an epitope at the N-terminal end of p53 between amino acids 20-25, binding to both wild type and mutant forms.

Summary This MAb reacts with an N-terminal epitope (aa 16-25) of both wild type and mutated p53.
We do not recommend use of this product for Mouse,Rat.

Summary This MAb is specific to c-erbB-2/HER-2 and shows minimal cross-reaction with other members of the family.