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Summary This antibody specifically interacts with the trimeric structure of laminin-511 isoform but does not react with any of the alpha 5, beta 1 and gamma 1 chains in the reducing conditions. Furthermore, it has been validated that clone 12D does not react with any of laminins-111, -211, -332, -3B32, -411 and -521. Unlike conventional anti- alpha 5 antibodies, clone 12D distinguishes laminin-511 from laminin-521.

Merlin (phospho Ser518) antibody Cat No. GTX22478

Orthogonal

Summary This phospho-specific polyclonal antibody is specific for phosphorylated pS518 of human NF2 (neurofibromatosis 2 gene product).   Reactivity with non-phosphorylated Human NF2 (Merlin) is minimal by ELISA.