1756

Summary This antibody reacts strongly with the carboxy terminus (between amino acids 3669 and 3685) of human dystrophin.No cross-reactivity with mdx mouse tissue. Cross reacts very weakly with pig dystrophin.

Summary This antibody reacts strongly with the rod domain (between amino acids 1181 and 1388) of human dystrophin. No reactivity with mdx mouse tissue of DMD/BMD patients who have a gene deletion which removes the antibody binding site.
We do not recommend use of this product for Chicken.

Summary This antibody reacts strongly with the amino terminal domain (between amino acids 321 and 494) of human dystrophin. Patient immunoreactivity indicates epitope is near exons 10 to 12. Epitope mapping suggests that sequences from amino acids 308 to 351 are involved in antibody binding. This region spans the junction of exons 9 and 10 and the epitope recognised may be part of a hinge region joining the amino domain to the central rod domain. No reactivity with DMD/BMD patients deleted for exons 10 to 12.
We do not recommend use of this product for Mouse,Rat,Rabbit,Dog,Hamster,Chicken,Pig.