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Virus Entry

Infection by animal viruses is initiated by viral binding to host cells. Delineation of the mechanisms mediating subsequent viral entry is an area of intense research, as there is considerable complexity and variability among different viruses. Nevertheless, a general framework for this process, particularly for some enveloped viruses, involves the following steps: (1) viral attachment to host cell receptors, (2) cell signaling pathway activation, (3) endocytosis, (4) penetration of cellular membranes and intracellular trafficking, and (5) viral genome uncoating. The viral genome is then available for expression, replication, packaging and release to infect other cells. Understanding the molecular events underlying virus/host cell interactions during entry is of paramount importance for the potential identification of targets for pharmacologic intervention.

GeneTex is proud to offer an outstanding selection of antibodies to study virus attachment, internalization and penetration for infectious disease research. These antibodies are validated for various applications to facilitate your efforts in this exciting field. Please see the highlighted products below or go to our website (www.genetex.com).

Highlighted Products
   
ACE2 antibody [N1N2], N-term (GTX101395)

ACE2 antibody [N1N2], N-term (GTX101395)

TMPRSS2 antibody [N2C3] (GTX100743)

TMPRSS2 antibody [N2C3] (GTX100743)

 
AXL antibody (GTX129407)

AXL antibody
(GTX129407)

CD13 antibody (GTX102788)

CD13 antibody
(GTX102788)

ICAM1 / CD54 antibody [N1C2] (GTX100450)

ICAM1 / CD54 antibody [N1C2] (GTX100450)

Occludin antibody (GTX114949)

Occludin antibody
(GTX114949)

 

Literature

Brochure - Antibodies For Virology Research

Download the latest version of GeneTex's Antibodies For Virology Research brochure.
Literature
Brochure - SARS-CoV-2 (COVID-19) Research

Brochure - SARS-CoV-2 (COVID-19) Research

Download the latest version of GeneTex's SARS-CoV-2 (COVID-19) Research brochure.
Literature

Flyer-Total Solutions of Antibodies for SARS CoV-2

Download the latest version of GeneTex's Total Solutions of Antibodies for SARS CoV-2 flyer.
Newsletter
Article alert: Proteomic Analysis Reveals How RNA Viruses Remodel Host Polysomes

Article alert: Proteomic Analysis Reveals How RNA Viruses Remodel Host Polysomes

Article alert: Proteomic Analysis Reveals How RNA Viruses Remodel Host Polysomes
Newsletter
Influenza A and B Virus Recombinant Monoclonal Antibodies

Influenza A and B Virus Recombinant Monoclonal Antibodies

Influenza A and B Virus Recombinant Monoclonal Antibodies
Literature
Pamphlet - SARS-CoV-2 (COVID-19) Research Reagents

Pamphlet - SARS-CoV-2 (COVID-19) Research Reagents

SARS-CoV-2 (COVID-19) Research Reagents
Newsletter
GeneTex’s SARS-CoV-2 Spike RBD Antibodies Effectively Inhibit Viral Entry

GeneTex’s SARS-CoV-2 Spike RBD Antibodies Effectively Inhibit Viral Entry

GeneTex’s SARS-CoV-2 Spike RBD Antibodies Effectively Inhibit Viral Entry
Newsletter

Neuropilins Facilitate SARS-CoV-2 Entry into Host Cells

Neuropilins Facilitate SARS-CoV-2 Entry into Host Cells
Newsletter

Zika Virus Infection Increases Risk of Subsequent Severe Dengue Disease

Zika Virus Infection Increases Risk of Subsequent Severe Dengue Disease
Newsletter
IHC- and FCM-validated Antibodies for SARS-CoV-2 Research

IHC- and FCM-validated Antibodies for SARS-CoV-2 Research

IHC- and FCM-validated Antibodies for SARS-CoV-2 Research
Newsletter
Spike Antibody-mediated Neutralization of SARS-CoV-2

Spike Antibody-mediated Neutralization of SARS-CoV-2

Spike Antibody-mediated Neutralization of SARS-CoV-2
Articles

The concept of a SARS-CoV-2 / COVID-19 rapid test

A rapid virus antigen test detects SARS-CoV-2 particles in samples by capturing viral antigen between a free labeled antibody and a fixed second antibody that each recognize different regions of the antigen.
Literature
Download the latest version of GeneTex's Zika Virus Research flyer.

Flyer-ZikaVirusResearch

Download the latest version of GeneTex's Zika Virus Research flyer.
Articles
SARS-CoV-2 (COVID-19) Spike Variant Recombinant Proteins

SARS-CoV-2 (COVID-19) Spike Variant Recombinant Proteins

Literature
Selected Antibodies for Influenza Virus

Flyer-Selected Antibodies for Influenza Virus

Download the latest version of GeneTex's Selected Antibodies for Influenza Virus flyer.
Literature

Flyer - Virus Entry into Host Cells

Download the latest version of GeneTex's Virus entry into host cells flyer.
Literature
Cited Antibodies

Flyer - Cited Antibodies

Download the latest version of GeneTex's cited antibodies flyer.
Literature

Brochure - Antibodies For Virology Research

Download the latest version of GeneTex's Antibodies For Virology Research brochure.
Literature
Brochure - SARS-CoV-2 (COVID-19) Research

Brochure - SARS-CoV-2 (COVID-19) Research

Download the latest version of GeneTex's SARS-CoV-2 (COVID-19) Research brochure.
Literature

Flyer-Total Solutions of Antibodies for SARS CoV-2

Download the latest version of GeneTex's Total Solutions of Antibodies for SARS CoV-2 flyer.
Literature
Pamphlet - SARS-CoV-2 (COVID-19) Research Reagents

Pamphlet - SARS-CoV-2 (COVID-19) Research Reagents

SARS-CoV-2 (COVID-19) Research Reagents
Literature
Download the latest version of GeneTex's Zika Virus Research flyer.

Flyer-ZikaVirusResearch

Download the latest version of GeneTex's Zika Virus Research flyer.
Literature
Selected Antibodies for Influenza Virus

Flyer-Selected Antibodies for Influenza Virus

Download the latest version of GeneTex's Selected Antibodies for Influenza Virus flyer.
Literature

Flyer - Virus Entry into Host Cells

Download the latest version of GeneTex's Virus entry into host cells flyer.
Literature
Cited Antibodies

Flyer - Cited Antibodies

Download the latest version of GeneTex's cited antibodies flyer.