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Summary The monoclonal antibody 80M2 recognizes the extracellular part of membrane-bound TNF-RII as well as the soluble form of TNF-RII which is generated by proteolytic cleavage of the extracellular domain. The soluble form can still bind TNF-alpha with high affinity and functions as a TNF-alpha antagonist. The antibody is a non-agonistic receptor modulating antibody. It enhances in vitro TNF alpha responses by increasing the affinity of the soluble form of TNF-alpha for TNF-RII.

Summary This antibody specifically recognizes the 85 kDa fragment of cleaved PARP and can be used as a marker for detecting apoptotic cells.

Summary This antibody recognizes defined epitope (aa 16-25) on human p53.

Summary At least two isoforms are known to exist; this antibody will detect both isoforms.

Summary This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein.
We do not recommend use of this product for Mouse,Rat.

Summary A lower but much weaker band at 30 kDa was detected in Raji cell lysate, which may represent the short form of Livin.

Summary NOD2 has no cross-reaction with NOD1.