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Summary This antibody stains mature monocyte - derived dendritic cells and weakly stains some peripheral blood mononuclear cells. Clone MG38 also stains cortical epithelium in the thymus.

Summary This antibody reacts with all forms of CD45.

Summary The monoclonal antibody JL-1 is reactive with the collagen-like region (CLR) only, which is the same region to which autoantibodies in mice and humans are binding. Anti-C1q autoantibodies deposit in glomeruli together with C1q but induce overt renal disease only in the context of glomerular immune complex disease. This provides an explanation why anti-C1q antibodies are especially pathogenic in patients with SLE.