Search Results

Summary The monoclonal antibody HM102 recognizes the extracellular part of membrane-bound TNF-RII as well as the soluble form of TNF-RII which is generated by proteolytic cleavage of the extracellular domain. The soluble form can still bind TNF-alpha with high affinity and functions as a TNF-alpha antagonist. The antibody is a agonistic receptor modulating antibody. It enhances in vitro TNF alpha responses by increasing the affinity of the soluble form of TNF-alpha for TNF-RII.

Summary React with caspase-2L p12 subunit and precursor (also designated Ich-1L).

Summary This antibody recognizes the extracellular domain of CD120a. The antibody blocks biological activity of both natural and recombinant human TNF alpha and TNF beta.

Summary This antibody reacts strongly in immunoblotting with fragments corresponding to peptide 319-572aa of Lamin C. When tested against nuclear protein extracts from HeLa cells it reacts with a single band migrating at 65 kDa. Stains lamin C from human, mouse and rat material

Summary This antibody recognizes neuraminidase-sensitive epitope on CD43 (Leukosialin).

Summary This antibody recognizes an epitope at the N-terminal end of p53 between amino acids 20-25,common to isoforms 1-3 of p53.