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BRCA1 antibody [17F8] - ChIP grade Cat No. GTX70111

27 References

KO/KD Orthogonal

Summary This antibody does not recognize the delta exon 11 splice variant of BRCA1. In a high proportion of breast and ovarian cancer cell lines, BRCA1 aberrantly mislocates to the cytoplasm.

Estrogen Receptor alpha antibody Cat No. GTX127978

3 References

Comparison Orthogonal Overexpression

Summary This antibody is specific for ER alpha protein, and it does not cross react with ER beta protein.

BRCA1 antibody [8F7] Cat No. GTX70113

16 References

KO/KD

Summary This antibody recognizes full-length BRCA1, a 220-kDa nuclear phosphoprotein. Mutations in this tumor suppressor gene greatly increase the risk of breast cancer.
KO/KD validation is based on published data (PMID: 23805307).

Estrogen Receptor alpha antibody [1F3] Cat No. GTX70171

7 References

Comparison Orthogonal Overexpression

Summary This antibody is specific for ER alpha protein, and it does not cross react with ER beta protein.

p53 (phospho Ser15) antibody Cat No. GTX21431

7 References

Orthogonal

Summary The phospho-p53 (Ser15) antibody detects ~53 kDa phosphorylated p53 at Ser15. It does not react with non-phosphorylated p53 or p53 phosphorylated at other sites.