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Angiogenesis

Angiogenesis entails the generation of new blood vessels from pre-existing vasculature. It is an intricate process tightly regulated by input from pro- and anti-angiogenic factors. In the normal adult, the balance between these inducers and inhibitors maintains a quiescent state that nevertheless is capable of rapid changes in response to micro-environmental disruptions secondary to wounds, hypoxia, or inflammation. Perturbations of this balance in various chronic pathological conditions and tumors can lead to inappropriate angiogenesis or neovascularization.

The mechanistic features underlying angiogenesis are complex, but the clinical importance of being able to modulate this process means that this will remain a compelling and dynamic field of research.

Highlighted Products

     

VEGF antibody (GTX102643)

 

VEGF antibody [VG1] (GTX21316)

VEGF Receptor 2 antibody (GTX129943)

 
 

Angiopoietin 2 antibody (GTX100928)

TIE1 antibody (GTX107818)

 

TIE2 antibody (GTX107505)

 
 
Cat. No. Product Name Host & Clonality Reactivity Applications  
GTX102643 VEGF antibody Rb pAb Hu, Ms, Rat IHC-P, WB  
GTX129844 VEGF antibody Rb pAb Hu WB
GTX74091 VEGF antibody Rb pAb Ms ELISA, ICC/IF, IHC-P, WB, Functional Assay
GTX21316 VEGF antibody [VG1] Ms mAb Hu, Ms, Rat ELISA, ICC/IF, IHC-Fr, IHC-P, WB
GTX16404 VEGFB antibody Rb pAb Hu, Ms, Rat IHC-P, WB  
GTX113574 VEGFC antibody Rb pAb Hu, Ms, Rat IHC-P, WB   
GTX59914 VEGFC antibody Rb pAb Hu WB
GTX100805 VEGFD antibody [N3C3] Rb pAb Hu IHC-P, WB  
GTX113695 VEGFD antibody Rb pAb Hu IHC-P, WB  
GTX128969 VEGF Receptor 1 antibody Rb pAb Hu WB  
GTX22350 VEGF Receptor 1 antibody Rb pAb Hu, Ms, Rat IHC, IHC-Fr, IHC-P  
GTX32184 VEGF Receptor 1 (phospho Tyr1213) antibody Rb pAb Hu, Rat WB
GTX129943 VEGF Receptor 2 antibody Rb pAb Hu WB
GTX17530 VEGF Receptor 2 antibody Chk pAb Hu, Ms, Rat, Bov IHC, WB
GTX50432 VEGF Receptor 2 antibody Rb pAb Hu, Ms, Rat ICC/IF, IHC-P, WB  
GTX50153 VEGF Receptor 2 (phospho Tyr951) antibody Rb pAb Hu, Ms, Rat ICC/IF, IHC-P, WB
GTX25473 VEGF Receptor 2 (phospho Tyr1054/Tyr1059) antibody Rb pAb Hu, Ms FACS, ICC/IF, WB
GTX32403 VEGF Receptor 2 (phospho Tyr1175) antibody Rb pAb Hu, Ms ICC/IF, IHC-P, WB  
GTX100807 VEGF Receptor 3 antibody Rb pAb Hu, Ms WB
GTX17567 VEGF Receptor 3 antibody [818CT12.1.1] Ms mAb Hu, Rat FACS, IHC-P, WB  
GTX107818 TIE1 antibody Rb pAb Hu, Ms IHC-P, WB  
GTX103429 TIE1 antibody Rb pAb Hu IHC-P, WB  
GTX107505 TIE2 antibody Rb pAb Hu IHC-P, WB
GTX107838 TIE2 antibody [C1C3] Rb pAb Hu, Ms IHC-P, WB  
GTX55336 TIE2 (phospho Tyr992) antibody Rb pAb Hu WB  
GTX121937 AKT antibody [N3C2], Internal Rb pAb Hu, Ms, Rat ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB    
GTX28933 AKT (phospho Thr308) antibody Rb pAb Hu, Ms, Rat ELISA, FACS, WB
GTX133175 AKT (phospho Thr450) antibody Rb pAb Hu, Ms, Rat WB
GTX128414 AKT (phospho Ser473) antibody Rb pAb Hu, Ms, Rat IHC-P, IP, WB  
GTX132615 AKT (phospho Ser473) antibody Rb pAb Hu, Ms, Rat WB
GTX28451 Angiopoietin 1 antibody Rb pAb Hu, Ms ELISA, IHC-P, WB
GTX28452 Angiopoietin 2 antibody Rb pAb Hu, Ms ELISA, IHC-P, WB
GTX100991 Angiopoietin 2 antibody Rb pAb Hu, Ms ICC/IF, IHC-P, WB  
GTX100928 Angiopoietin 2 antibody Rb pAb Hu, Ms IHC-P, WB
GTX129407 AXL antibody Rb pAb Hu ELISA, IHC-P, WB  
GTX101345 AXL antibody [C2C3], C-term Rb pAb Hu IHC-P, WB   
GTX132386 AXL antibody Rb pAb Hu WB  
GTX632645 CD31 antibody [GT0010] Ham mAb Ms, Rat FACS, IHC-P
GTX110602 CD31 antibody [N3C2], Internal Rb pAb Hu IHC-P, WB  
GTX130274 CD31 antibody Rb pAb Ms IHC-P, WB
GTX20218 CD31 antibody [WM59] Ms mAb Hu, Ms, RMK, ClMK FACS, ICC/IF, IHC, IHC-Fr, IHC-P, IP, IHC-Wm
GTX100904 CDC42 antibody Rb pAb Ms, Rat IHC-P, WB
GTX134588 CDC42 antibody Rb pAb Hu WB
GTX100656 COX2 antibody [C3], C-term Rb pAb Hu, Ms, Rat IHC-P, WB  
GTX129843 eNOS antibody Rb pAb Hu ICC/IF, WB
GTX133404 eNOS antibody Rb pAb Hu WB
GTX83305 eNOS antibody [6H2] Ms mAb Hu ELISA, IHC-P
GTX129058 eNOS (phospho Ser1177) antibody Rb pAb Hu, Ms, Rat IHC-P, WB  
GTX100699 ERK1 antibody Rb pAb Hu WB
GTX113094 ERK2 antibody [N2C3] Rb pAb Hu, Ms, Pig, Rat IHC-P, IP, WB   
GTX134462 ERK1/2 antibody Rb pAb Hu WB  
GTX82780 FAK antibody [10H7] Ms mAb Hu, Ms ELISA, ICC/IF, IHC-P, WB  
GTX129840 FAK (phospho Tyr397) antibody Rb pAb Hu, Ms, Rat ICC/IF, IHC-P, WB   
GTX132320 FAK (phospho Tyr407) antibody Rb pAb Hu, Ms, Rat ICC/IF, WB  
GTX132140 FAK (phospho Tyr576) antibody Rb pAb Hu, Ms, Rat ICC/IF, WB  
GTX24804 FAK (phospho Tyr861) antibody Rb pAb Hu, Ms, Chk, Dog, Rat, Zfsh, Amph, Hm, Xenopus ICC/IF, IHC, IHC-P, IP, WB
GTX81891 FGF1 antibody, N-term Rb pAb Hu ICC/IF, IHC-P, WB  
GTX84502 FGF2 antibody [3D9] Ms mAb Hu, Mk ICC/IF, IHC-P, WB
GTX111253 GAB1 antibody Rb pAb Hu, Ms IHC-P, WB  
GTX114226 GAB2 antibody [N1C1] Rb pAb Hu WB  
GTX39987 Integrin alpha V + beta 5 antibody [P1F6] Ms mAb Hu, Chk ELISA, FACS, ICC/IF, IHC-Fr, IP  
GTX100789 Integrin alpha V antibody [C2C3], C-term Rb pAb Hu, Ms ELISA, IHC-P, WB  
GTX111672 Integrin beta 3 antibody [N2C1], Internal Rb pAb Hu WB  
GTX102680 Integrin beta 5 antibody [N1C1] Rb pAb Hu WB  
GTX104577 MMP2 antibody Rb pAb Hu, Ms ICC/IF, IHC-P, IP, WB
GTX634832 MMP2 antibody [GT185] Ms mAb Hu WB  
GTX100723 MMP3 antibody [N3C1], Internal Rb pAb Hu ICC/IF, IHC-P, WB
GTX103647 MMP3 antibody [N1C1] Rb pAb Hu, Bov IHC-P, WB
GTX100458 MMP9 antibody [N2C1], Internal Rb pAb Hu, Bov ICC/IF, IHC-P, WB  
GTX127932 NFAT1 antibody Rb pAb Hu, Ms ICC/IF, IP, WB  
GTX22722 NFAT1 antibody [25A10.D6.D2] Ms mAb Hu, Ms, Rat FACS, GSA, ICC/IF, IHC-Fr, IHC-P, IP, WB, ChIP assay  
GTX25246 NFAT1 (phospho Ser54) antibody Rb pAb Hu, Ms FACS, ICC/IF, WB  
GTX28925 NOTCH1 antibody Rb pAb Hu, Ms, Rat ELISA, ICC/IF, IHC-P, Neut, WB
GTX101593 NOTCH2 antibody [C2], C-term Rb pAb Hu, Ms WB, ChIP-seq
GTX127947 Neuropilin 1 antibody Rb pAb Ms, Rat IHC-P, WB  
GTX102397 NRP2 antibody [N2N3] Rb pAb Hu WB  
GTX110720 p38 MAPK antibody [N1C3-2] Rb pAb Hu, Ms, Rat ICC/IF, IHC-P, WB  
GTX133460 p38 MAPK (phospho Thr180/Tyr182) antibody Rb pAb Hu WB  
GTX125891 Paxillin antibody Rb pAb Hu, Ms, Rat ICC/IF, IHC-P, IP, WB   
GTX633769 Paxillin antibody [GT7612] Ms mAb Hu ICC/IF, WB
GTX132154 Paxillin (phospho Tyr31) antibody Rb pAb Hu ICC/IF, WB   
GTX132152 Paxillin (phospho Tyr118) antibody Rb pAb Hu, Ms, Rat ICC/IF, WB  
GTX633707 Paxillin (non-phospho Tyr118) antibody [GT722] Ms mAb Hu, Ms, Rat ICC/IF, WB  
GTX132362 Paxillin (phospho Ser273) antibody Rb pAb Hu, Ms WB
GTX107903 PDGF Receptor alpha antibody [N2C2], Internal Rb pAb Hu, Ms, Rat WB
GTX133588 PDGF Receptor alpha antibody Rb pAb Ms WB  
GTX133587 PDGF Receptor beta antibody Rb pAb Hu WB  
GTX100683 PDGF beta antibody Rb pAb Hu IHC-P, WB  
GTX54575 PDGF beta antibody Rb pAb Hu, Ms, Rat IHC-P, WB
GTX100462 PI3 kinase p110 alpha antibody Rb pAb Hu, Ms ICC/IF, IHC-P, WB
GTX111173 PI3 kinase p110 beta antibody [N3C2], Internal Rb pAb Hu, Ms, Rat ICC/IF, IHC-P, WB
GTX74710 PI3 kinase p85 beta antibody [T15] Ms mAb Hu, Mk, Bov IHC-Fr, IP, WB  
GTX50858 PI3 kinase p85 (phospho Tyr467)/p55 (phospho Tyr199) antibody Rb pAb Hu, Ms, Rat WB
GTX108953 PI3 kinase p150 antibody [C1C3] Rb pAb Hu IP, WB  
GTX132466 PI3 kinase p150 antibody Rb pAb Hu, Ms IHC-P, IP, WB
GTX133546 PLCG1 antibody Rb pAb Hu, Ms, Rat WB  
GTX133465 PLCG1 (phospho Tyr783) antibody Rb pAb Hu, Ms WB
GTX133466 PLCG1 (phospho Ser1248) antibody Rb pAb Hu WB
GTX32238 PLCG1 (phospho Tyr1253) antibody Rb pAb Hu, Ms, Rat ICC/IF, WB
GTX111293 PLCG2 antibody [N1N2], N-term Rb pAb Hu, Ms ICC/IF, IHC-P, WB  
GTX133463 PLCG2 (phospho Tyr759) antibody Rb pAb Hu WB
GTX133610 PLCG2 (phospho Tyr1217) antibody Rb pAb Hu, Ms WB
GTX13048 RAC antibody [23A8] Ms mAb Hu, Ms, Rat IHC-Fr, IP, WB  
GTX130671 Semaphorin 3A antibody Rb pAb Hu, Ms, Rat IHC-P, WB  
GTX130023 TGF beta 1 antibody Rb pAb Hu, Ms WB   
GTX134209 TGF beta Receptor I antibody Rb pAb Hu WB  
GTX129909 TGF beta Receptor II antibody Rb pAb Hu WB  
GTX109068 TGF beta Receptor III antibody Rb pAb Hu WB  

 

 

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