GeneTex
  • Country / Location Selection

United States (US)

DNA Methylation

The three mammalian 5-methylcytosine (5-mC) dioxygenases (Ten Eleven Translocation (TET); TET1, TET2, and TET3 in humans) convert 5-mC to 5-hydroxymethylcytosine (5-hmC) and subsequently to 5-formylcytosine (5-fC) and 5-carboxylcytosine (5-caC). This series of modifications is thought to represent one pathway to active DNA demethylation, thereby reshaping the methylated DNA landscape established by DNA methyltransferases (DNMTs). In addition, these marks, particularly 5-hmC, have been shown to be distinct epigenetic signatures in their own right impacting stem cell and cancer cell biology.

GeneTex introduces a selection of antibodies to targets relevant to DNA methylation and demethylation. We are proud to note that many of these antibodies are suitable for ChIP/ (h)MeDIP application.

 

See all related Products

 

Highlighted Products
  Orthogonal Validation Protein Overexpression 
TDG antibody (GTX110473)

TDG antibody (GTX110473)

DNMT1 antibody [N1], N-term (GTX116011)

DNMT1 antibody [N1], N-term (GTX116011)

TET2 antibody [N2-2], N-term (GTX124205)

TET2 antibody [N2-2], N-term (GTX124205)

 
DNMT3B antibody (GTX129127)

DNMT3B antibody (GTX129127)

SIN3A antibody (GTX129156)

SIN3A antibody (GTX129156)

TET1 antibody [GT1462] (GTX627420)

TET1 antibody [GT1462] (GTX627420)

 

 

 

Newsletter
Article Alert: Induced Proteasomal Degradation of TET2 Leads to EGFR-Tyrosine Kinase Inhibitor Resistance In Non-Small Cell Lung Cancer

Induced Proteasomal Degradation of TET2 Leads to EGFR-Tyrosine Kinase Inhibitor Resistance In NSCLC

Article Alert: Induced Proteasomal Degradation of TET2 Leads to EGFR-Tyrosine Kinase Inhibitor Resistance In Non-Small Cell Lung Cancer
Literature

Flyer - IVD-related Products

Download the latest version of GeneTex's IVD-related Products flyer.
Literature

Flyer - Cited Antibodies 2024 Q2

Download the latest version of GeneTex's Antibodies for Cited Antibodies 2024 Q2 flyer.
Articles

IVD-related Products and Services

Newsletter
Article Alert: Urothelial Epigenome Reprogramming by Uropathogenic E. coli Underlies Recurrent Urinary Tract Infection Susceptibility

Urothelial Epigenome Reprogramming by Uropathogenic E. coli Underlies Recurrent UTI Susceptibility

Article Alert: Urothelial Epigenome Reprogramming by Uropathogenic E. coli Underlies Recurrent Urinary Tract Infection Susceptibility
Newsletter

Lateral Flow Assay for Influenza & SARS-CoV-2 Viruses Detection

Influenza A & B Virus Antibodies (IVD grade)
Literature
Brochure - Cited Antibodies

Brochure - Cited Antibodies

Download the latest version of GeneTex's Cited Antibodies brochure.
Literature
Cited Antibodies

Flyer - Cited Antibodies

Download the latest version of GeneTex's cited antibodies flyer.
Literature
World Class Validated Antibodies

Brochure - World Class Validated Antibodies

Download the latest version of GeneTex's World Class Validated Antibodies brochure.
Literature
Epigenetics poster

Poster - Epigenetics

Download the latest version of GeneTex's Epigenetics poster
Literature
Epigenetics DNA Methylation

Flyer - Epigenetics DNA Methylation

Download the latest version of GeneTex's epigenetics DNA methylation flyer.
Literature

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.
Literature

Flyer - IVD-related Products

Download the latest version of GeneTex's IVD-related Products flyer.
Literature

Flyer - Cited Antibodies 2024 Q2

Download the latest version of GeneTex's Antibodies for Cited Antibodies 2024 Q2 flyer.
Literature
Brochure - Cited Antibodies

Brochure - Cited Antibodies

Download the latest version of GeneTex's Cited Antibodies brochure.
Literature
Cited Antibodies

Flyer - Cited Antibodies

Download the latest version of GeneTex's cited antibodies flyer.
Literature
World Class Validated Antibodies

Brochure - World Class Validated Antibodies

Download the latest version of GeneTex's World Class Validated Antibodies brochure.
Literature
Epigenetics poster

Poster - Epigenetics

Download the latest version of GeneTex's Epigenetics poster
Literature
Epigenetics DNA Methylation

Flyer - Epigenetics DNA Methylation

Download the latest version of GeneTex's epigenetics DNA methylation flyer.
Literature

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.