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Obesity

Obesity

Obesity is characterized by increased lipid accumulation in adipocytes, leading to white adipose tissue hypertrophy, impaired lipolysis, and ectopic fat deposition in other tissues. Adipocytes are also highly active secretory cells, producing proteins and hormones that function well beyond metabolism. The worldwide epidemic of obesity has led to a dramatic increase in metabolic diseases, including type 2 diabetes mellitus, nonalcoholic fatty liver disease, steatohepatitis, asthma, cancer, cardiovascular disease, and neurodegenerative diseases that are related to the generation of low‑grade, chronic inflammation. Type 2 diabetes is caused by obesity-driven insulin resistance in white adipose tissue, the liver, and skeletal muscle combined with impaired secretion of insulin by pancreatic β-cells. Understanding the molecular mechanisms that promote obesity-related diseases will accelerate the development of new therapeutic approaches for these often devastating conditions.

GeneTex is proud to offer an outstanding selection of antibodies to study adipogenesis, adipocyte biology, and insulin resistance signaling for obesity research. These antibodies are validated for various applications to facilitate your efforts in this exciting field. Please see the highlighted products below.

 

Highlighted Products
Citation Support KOKD Validation Orthogonal Validation Protein Overexpression

 

Adiponectin antibody

Adiponectin antibody
(GTX112777)

Citation Support Orthogonal Validation
Leptin antibody

Leptin antibody
(GTX109204)

Citation Support Protein Overexpression
Perilipin 1 antibody

Perilipin 1 antibody
(GTX130139)

Citation Support Orthogonal Validation
 
Fatty Acid Synthase antibody [N1], N-term

Fatty Acid Synthase antibody [N1], N-term
(GTX109833)

Citation Support KOKD Validation Orthogonal Validation
Apolipoprotein E antibody [C2C3], C-term

Apolipoprotein E antibody [C2C3], C-term
(GTX100053)

Citation Support
FABP4 antibody [N3C3]

FABP4 antibody [N3C3]
(GTX116036)

Citation Support Orthogonal Validation
 

 

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Lateral Flow Assay for Influenza & SARS-CoV-2 Viruses Detection

Influenza A & B Virus Antibodies (IVD grade)
Literature
Obesity & Diabetes

Flyer - Obesity & Diabetes

Download the latest version of GeneTex's Obesity & Diabetes flyer.
Literature
Obesity & Diabetes

Flyer - Obesity & Diabetes

Download the latest version of GeneTex's Obesity & Diabetes flyer.