Amyotrophic lateral sclerosis (ALS) is an invariably fatal adult-onset neurodegenerative disorder characterized by the progressive loss of both upper and lower motor neurons. The major clinical presentation of ALS is muscle weakness and atrophy affecting speech, swallowing, and movement, with respiratory failure being the most common reason for death usually within 3-5 years of diagnosis. Though the cause is unknown, recent studies have identified several genes associated with the disease including SOD1, TARDBP, FUS, C9orf72, C21orf2, and most recently NEK1.

GeneTex is proud to offer exceptional antibodies against these targets relevant to ALS. Please see the examples highlighted below and the accompanying table to find the reagent that facilitates your ALS research.

 

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C9orf72 antibody GTX634482	Nek1 antibody GTX130828	SOD1 antibody GTX100659	SOD1 (mutant) antibody GTX57211

TDP43 antibody GTX114210	VCP antibody GTX113030	C21orf2 antibody GTX119046	HSC70 antibody GTX111069