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Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is an invariably fatal adult-onset neurodegenerative disorder characterized by the progressive loss of both upper and lower motor neurons. The major clinical presentation of ALS is muscle weakness and atrophy affecting speech, swallowing, and movement, with respiratory failure being the most common reason for death usually within 3-5 years of diagnosis. Though the cause is unknown, recent studies have identified several genes associated with the disease including SOD1, TARDBP, FUS, C9orf72, C21orf2, and most recently NEK1.
 
GeneTex is proud to offer exceptional antibodies against these targets relevant to ALS. Please see the examples highlighted below and the accompanying table to find the reagent that facilitates your ALS research.

 

 

Highlighted Products:

  

C9orf72 antibody

C9orf72 antibody  (GTX634482)

Nek1 antibody

Nek1 antibody (GTX130828)

 
SOD1 antibody

SOD1 antibody (GTX100659)

 
SOD1 (mutant) antibody (GTX57211) 

SOD1 (mutant) antibody (GTX57211

 
TDP43 antibody

TDP43 antibody (GTX114210)

VCP antibody

VCP antibody  (GTX113030)

 
C21orf2 antibody [N1C2]

C21orf2 antibody (GTX119046)

 
HSC70 antibody

HSC70 antibody (GTX111069)

   

 

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GeneTex Antibody Trial Program - Try Before You Buy

GeneTex Antibody Trial Program - Try Before You Buy

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GeneTex Antibody Trial Program - Try Before You Buy

GeneTex Antibody Trial Program - Try Before You Buy

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GeneTex Antibody Trial Program - Try Before You Buy

GeneTex Antibody Trial Program - Try Before You Buy

Newsletter
GeneTex Introduces Recombinant Monoclonal Iba1 Antibody

GeneTex Introduces Recombinant Monoclonal Iba1 Antibody

GeneTex's Iba1 recombinant antibody is suitable for IHC staining and WB.
Newsletter
Independent Knockout Validation of C9ORF72 Antibodies

Independent Knockout Validation of C9ORF72 Antibodies

Independent Knockout Validation of C9ORF72 Antibodies for the research of Amyotrophic lateral sclerosis.
Newsletter
Is ApoE the piece to complete the puzzle of Alzheimer’s disease?

Is ApoE the piece to complete the puzzle of Alzheimer’s disease?

ApoE was identified as a major checkpoint inhibitor of the classical complement cascade, and involved in a possible unifying mechanism underlying Alzheimer’s disease, atherosclerosis, and potentially other inflammatory diseases.
Literature
Neurotransmission

Flyer - Neurotransmission

Download the latest version of GeneTex's Neurotransmission flyer.
Newsletter

Neurodegeneration: A "Vicious Cycle" Involving Mitochondria, Glia, and Neuronal Death

A "Vicious Cycle" Involving Mitochondria, Glia, and Neuronal Death
Newsletter

Clinical trials targeting alpha-synuclein protein in Parkinson’s disease

α-synuclein has become a major therapeutic target in PD. Multiple clinical trials are ongoing.
Literature
Recombinant Active Proteins

Pamphlet - Recombinant Active Proteins

Download the latest version of GeneTex's Recombinant Active Proteins Pamphlet.
Literature
World Class Validated Antibodies

Brochure - World Class Validated Antibodies

Download the latest version of GeneTex's World Class Validated Antibodies brochure.
Literature
Neuroinflammation

Flyer - Neuroinflammation

Download the latest version of GeneTex's Neuroinflammation flyer.
Articles
beta Amyloid

beta Amyloid

GeneTex’s “beta-Amyloid (1-42) antibody – Conformation-Specific” can specifically detect amyloid plaques in the Alzheimer's Disease brain by IHC-P analysis. The superior specificity and sensitivity of this antibody were confirmed by dot blot, ELISA and side-by-side IHC-P comparison with competitor's.
Literature

Pamphlet - Neuroscience Research

Download the latest version of GeneTex's neuroscience research pamphlet.
Literature

Flyer - Amyotrophic Lateral Sclerosis

Download the latest version of GeneTex's amyotrophic lateral sclerosis flyer.
Literature

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.
Literature
Neurotransmission

Flyer - Neurotransmission

Download the latest version of GeneTex's Neurotransmission flyer.
Literature
Recombinant Active Proteins

Pamphlet - Recombinant Active Proteins

Download the latest version of GeneTex's Recombinant Active Proteins Pamphlet.
Literature
World Class Validated Antibodies

Brochure - World Class Validated Antibodies

Download the latest version of GeneTex's World Class Validated Antibodies brochure.
Literature
Neuroinflammation

Flyer - Neuroinflammation

Download the latest version of GeneTex's Neuroinflammation flyer.
Literature

Pamphlet - Neuroscience Research

Download the latest version of GeneTex's neuroscience research pamphlet.
Literature

Flyer - Amyotrophic Lateral Sclerosis

Download the latest version of GeneTex's amyotrophic lateral sclerosis flyer.
Literature

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.