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Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is an invariably fatal adult-onset neurodegenerative disorder characterized by the progressive loss of both upper and lower motor neurons. The major clinical presentation of ALS is muscle weakness and atrophy affecting speech, swallowing, and movement, with respiratory failure being the most common reason for death usually within 3-5 years of diagnosis. Though the cause is unknown, recent studies have identified several genes associated with the disease including SOD1, TARDBP, FUS, C9orf72, C21orf2, and most recently NEK1.

GeneTex is proud to offer exceptional antibodies against these targets relevant to ALS. Please see the examples highlighted below and the accompanying table to find the reagent that facilitates your ALS research.

See all related Products

Highlighted Products
   
C9orf72 antibody

C9orf72 antibody  (GTX634482)

Nek1 antibody

Nek1 antibody (GTX130828)

SOD1 antibody

SOD1 antibody (GTX100659)

 
SOD1 (mutant) antibody (GTX57211) 

SOD1 (mutant) antibody (GTX57211) 

 
TDP43 antibody

TDP43 antibody (GTX114210)

VCP antibody

VCP antibody  (GTX113030)

 
C21orf2 antibody [N1C2]

C21orf2 antibody (GTX119046)

 
HSC70 antibody

HSC70 antibody (GTX111069)

   

 

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Article Alert: Reactive Astrocyte-Secreted HSPB1 is Neuroprotective in Alzheimer's disease

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Influenza A & B Virus Antibodies (IVD grade)
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