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Summary This antibody was raised against human CD19 Intracellular domain.

Summary The Binding of EDHu-1 occurs via the N-terminal region of CD163 containing the first three scavenger receptor, Cysteine-rich, SRCR domains the third domain being critical as, cleavage of this domain at the major cleavage site ASP-265 abrogates binding to the N-terminal fragment.

IL1 beta antibody Cat No. GTX22105

4 References

Orthogonal

Summary Primarily directed against mature 17kDa human IL-1beta. In ELISA formats and other immunoreactive assays, the antibody will recognize 10% of the non-denatured (native) 31kDa IL-1beta precursor containing samples, but will detect all of the 17kDa mature molecule. Also detects primate IL-1beta in the same formats using similar dilutions.The antiserum does not recognize human IL-1alpha.

ETEA antibody [N3C3] Cat No. GTX115680

3

KO/KD

Summary KO/KD validation is based on customer review data.