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Hypoxia

Hypoxia
 

The development of complex anatomical and physiological systems to maintain oxygen homeostasis was an essential process in the evolution of metazoans. Hypoxia, defined as an insufficient oxygen supply to tissues, elicits a cellular response that hinges on the stabilization of hypoxia-inducible factors (HIFs). These transcription factors are subsequently able to accumulate in the nucleus and bind to DNA at “hypoxia response elements” (HREs) and subsequently drive either the expression (or, perhaps indirectly, the repression) of hundreds of genes.

Highlighted Products

      
HIF1 alpha antibody
(GTX628480)

HIF1 alpha antibody
(GTX628480)

 
HIF1 beta antibody
(GTX128795)

HIF1 beta antibody
(GTX128795)

HIF2 alpha antibody
(GTX632015)

HIF2 alpha antibody
(GTX632015)

 
 
 
CAIX antibody
(GTX70020)

CAIX antibody
(GTX70020)

 
Heme Oxygenase 1 antibody
(GTX101147)

Heme Oxygenase 1 antibody
(GTX101147)

  
PHD2 antibody
(GTX132293)

PHD2 antibody
(GTX132293)

 
 
 
PKM antibody
(GTX107977)

PKM antibody
(GTX107977)

  
MMP2 antibody
(GTX104577)

MMP2 antibody
(GTX104577)

 
VEGF antibody
(GTX102643)

VEGF antibody
(GTX102643)

  
 
 
VE-cadherin antibody
(GTX633705)

VE-cadherin antibody
(GTX633705)

 
mTOR antibody (GTX101557)

mTOR antibody
(GTX101557)

 
AKT (pSer473) antibody (GTX128414)

AKT (pSer473) antibody
(GTX128414)

 
 
 
PHD1 antibody
(GTX123033)

PHD1 antibody
(GTX123033)

 
PHD4 antibody
(GTX116582)

PHD4 antibody
(GTX116582)

 
VHL antibody
(GTX101087)

VHL antibody
(GTX101087)

 
 
 
PD-L1 antibody
(GTX104763)

PD-L1 antibody
(GTX104763)

   
     

 

 

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Download the latest version of GeneTex's hypoxia markers poster
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Brochure - World Class Validated Antibodies

Download the latest version of GeneTex's World Class Validated Antibodies brochure.
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Download the latest version of GeneTex's cancer signaling poster
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Download the latest version of GeneTex's RNA-binding proteins flyer.
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Download the latest version of GeneTex's pamphlet of hot products.
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Download the latest version of GeneTex's pamphlet of antibodies for cancer research
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Poster - Hypoxia Regulation

Download the latest version of GeneTex's hypoxia regulation poster
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Flyer - Hypoxia Markers

Download the latest version of GeneTex's hypoxia markers poster