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RAS (G12D Mutant) antibody [HL10] Cat No. GTX635362

5 18 References

Recombinant antibody Orthogonal Overexpression

Summary Based on internal testing, this antibody specifically recognizes RAS G12D mutant and does not cross-react with wild-type RAS or the G12V, G12R, G12C, G12A, or G12S mutants.

RAS (G12V Mutant) antibody [HL169] Cat No. GTX635623

1 References

Recombinant antibody Orthogonal Overexpression

Summary Based on internal testing, this antibody specifically recognizes RAS G12V mutant and does not cross-react with wild-type RAS or the G12D, G12R, G12C, G12A, or G12S mutants.

RAS (G12D Mutant) antibody [HL2640] Cat No. GTX639096

Recombinant antibody Orthogonal Overexpression

Summary Based on internal testing, this antibody specifically recognizes RAS G12D mutant and does not cross-react with wild-type RAS or the G12V, G12R, G12C, G12A, or G12S mutants.

RAS (G12A mutant) antibody [HL1153] Cat No. GTX636434

Recombinant antibody Orthogonal Overexpression

Summary This antibody was raised against RAS G12A mutant. Based on in-house and independent lab testing, it also cross-reacts with RAS G12S and Wide type , but does not react with RAS G12D, G12V, G12R, and G12C mutants. Cross-reactivity with wild-type RAS has only been observed under conditions of overexpression and is not detected at endogenous levels.

Hsp70 antibody Cat No. GTX111088

5 12 References

KO/KD

Summary KO/KD validation is based on published data (PMID: 26863132).