Search Results

Summary Recognizes the CD28 (44 kDa) human cell surface disulfide-linked, homodimeric glycoprotein. The antibody reacts with human CD28-transfected murine T-cell hybridoma, PHA-activated blasts and IL-6 dependent plasmacytoma lines. It cross reacts with rhesus monkey PBL. The antibody blocks CD28/B7 (CD80) mediated cell-cell adhesion. It binds to the CDR domain in a CDR1 dependent manner. It enhances CD3 monoclonal antibody-induced T-cell proliferation. May be used in adhesion and co-stimulation studies.

EphA4 antibody [N3C2-2], Internal GTX111602

1 References 2

Overexpression

Summary Based on internal testing result, this antibody may cross react with EphA5, EphA6, and EphA7.

GSTT1 antibody GTX109250

References 1

KO/KD

Summary KO/KD validation is based on published data (PMID: 30446643).

BRCA1 antibody [6B4] - ChIP grade GTX70115

References 3

KO/KD

Summary This antibody recognizes BRCA1, a 220-kDa nuclear phosphoprotein, and does not recognize the exon 11 splice variant. Mutations in this tumor suppressor gene greatly increase the risk of breast cancer.