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Summary This antibody detects both the steroid occupied and unoccupied forms of the estrogen receptor (ER) alpha from human samples. It detects ER alpha and does not cross react with ER beta.

Summary The Binding of EDHu-1 occurs via the N-terminal region of CD163 containing the first three scavenger receptor, Cysteine-rich, SRCR domains the third domain being critical as, cleavage of this domain at the major cleavage site ASP-265 abrogates binding to the N-terminal fragment.