Oncoproteins

The products of metazoan cell proto-oncogenes are generally key constituents of the cell signaling and gene expression machinery that regulate cell growth and proliferation. When mutated, amplified, or otherwise expressed in a dysregulated manner, these genes can become cellular oncogenes and their oncoprotein products drive tumorigenic cell growth. Examples of proto-oncogenes include the RAS genes, ERBB2, MYC, and ABL1. Certain viruses, or oncoviruses, have the capability to cause cancers through the action of viral genome-encoded oncoproteins that target metazoan cell factors or pathways.

 

 

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B-Raf (V600E Mutant) antibody [HL5673] GTX646482	RAS (G12D Mutant) antibody [HL10] GTX635362	Her2 / ErbB2 (phospho Tyr1248) antibody [HL1466] GTX636940	EGFR antibody [HL1097] GTX642543

Claudin 18.2 antibody [HL5230] GTX645486	TACSTD2 antibody [HL5900] GTX647224	c-Myc antibody [HL6095] GTX648180	BCL6 antibody [HL2192] GTX638196