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Oncoproteins

Oncoproteins

Oncoproteins

The products of metazoan cell proto-oncogenes are generally key constituents of the cell signaling and gene expression machinery that regulate cell growth and proliferation. When mutated, amplified, or otherwise expressed in a dysregulated manner, these genes can become cellular oncogenes and their oncoprotein products drive tumorigenic cell growth. Examples of proto-oncogenes include the RAS genes, ERBB2, MYC, and ABL1. Certain viruses, or oncoviruses, have the capability to cause cancers through the action of viral genome-encoded oncoproteins that target metazoan cell factors or pathways.
Highlighted Products
 

 

AKT antibody [N3C2], Internal

AKT antibody
(GTX121937)
Ras antibody

Ras antibody
(GTX132480)
Aurora B antibody

Aurora B antibody
(GTX130211)

 

VEGF antibody

VEGF antibody
(GTX102643)
EGFR antibody [N1-2], N-term

EGFR antibody
(GTX121919)
Phospho-EGF Receptor (Tyr1068) antibody

Phospho-EGF Receptor (Tyr1068) antibody
(GTX132810)
Her2 / ErbB2 antibody [C2C3], C-term

Her2 / ErbB2 antibody
(GTX100509)
Her2 / ErbB2 (phospho Tyr1221/Tyr1222) antibody

Her2 / ErbB2 (phospho Tyr1221/Tyr1222) antibody
(GTX133445)
PDGF Receptor beta (phospho Tyr751) antibody

PDGF Receptor beta (phospho Tyr751) antibody
(GTX133525)
Literature
World Class Validated Antibodies

Brochure - World Class Validated Antibodies

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Pathways

Wnt Pathway

Wnt proteins are secreted morphogens that are required for various developmental processes.
Literature
Cancer Signaling

Poster - Cancer Signaling

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Literature

Flyer - EGFR Signaling

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Literature

Flyer - RNA-binding Proteins

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Literature

Pamphlet - Hot Products

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Literature

Pamphlet - Antibodies for Cancer Research

Download the latest version of GeneTex's pamphlet of antibodies for cancer research
Literature
World Class Validated Antibodies

Brochure - World Class Validated Antibodies

Download the latest version of GeneTex's World Class Validated Antibodies brochure.
Literature
Cancer Signaling

Poster - Cancer Signaling

Download the latest version of GeneTex's cancer signaling poster
Literature

Flyer - EGFR Signaling

Download the latest version of GeneTex's EGFR signaling flyer.
Literature

Flyer - RNA-binding Proteins

Download the latest version of GeneTex's RNA-binding proteins flyer.
Literature

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.
Literature

Pamphlet - Antibodies for Cancer Research

Download the latest version of GeneTex's pamphlet of antibodies for cancer research