Oncoproteins

 

The products of metazoan cell proto-oncogenes are generally key constituents of the cell signaling and gene expression machinery that regulate cell growth and proliferation. When mutated, amplified, or otherwise expressed in a dysregulated manner, these genes can become cellular oncogenes and their oncoprotein products drive tumorigenic cell growth. Examples of proto-oncogenes include the RAS genes, ERBB2, MYC, and ABL1. Certain viruses, or oncoviruses, have the capability to cause cancers through the action of viral genome-encoded oncoproteins that target metazoan cell factors or pathways.

 

 

 

AKT antibody [N3C2], Internal

AKT antibody

Ras antibody

Ras antibody

Aurora B antibody

Aurora B antibody

VEGF antibody

       
EGFR antibody [N1-2], N-term

EGFR antibody

Phospho-EGF Receptor (Tyr1068) antibody

Her2 / ErbB2 antibody [C2C3], C-term

Her2 / ErbB2 antibody

Her2 / ErbB2 (phospho Tyr1221/Tyr1222) antibody

Her2 / ErbB2 (phospho Tyr1221/Tyr1222) antibody

       

PDGF Receptor beta (phospho Tyr751) antibody

PDGF Receptor beta (phospho Tyr751) antibody