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Oncoproteins

Oncoproteins

The products of metazoan cell proto-oncogenes are generally key constituents of the cell signaling and gene expression machinery that regulate cell growth and proliferation. When mutated, amplified, or otherwise expressed in a dysregulated manner, these genes can become cellular oncogenes and their oncoprotein products drive tumorigenic cell growth. Examples of proto-oncogenes include the RAS genes, ERBB2MYC, and ABL1. Certain viruses, or oncoviruses, have the capability to cause cancers through the action of viral genome-encoded oncoproteins that target metazoan cell factors or pathways.

Highlighted Products
Citation Support  KOKD Validation  Comparable Abs  IP/MS Analysis  Orthogonal Validation  Protein Overexpression

 

AKT antibody [N3C2], Internal

AKT antibody
(GTX121937)

Ras antibody

Ras antibody
(GTX132480)

Aurora B antibody

Aurora B antibody
(GTX130211)

 

VEGF antibody

VEGF antibody
(GTX102643)

EGFR antibody [N1-2], N-term

EGFR antibody
(GTX121919)

Phospho-EGF Receptor (Tyr1068) antibody

Phospho-EGF Receptor (Tyr1068) antibody
(GTX132810)

Her2 / ErbB2 antibody [C2C3], C-term

Her2 / ErbB2 antibody
(GTX100509)

Her2 / ErbB2 (phospho Tyr1221/Tyr1222) antibody

Her2 / ErbB2 (phospho Tyr1221/Tyr1222) antibody
(GTX133445)

PDGF Receptor beta (phospho Tyr751) antibody

PDGF Receptor beta (phospho Tyr751) antibody
(GTX133525)

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Flyer - EGFR Signaling

Download the latest version of GeneTex's EGFR signaling flyer.
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Lateral Flow Assay for Influenza & SARS-CoV-2 Viruses Detection

Influenza A & B Virus Antibodies (IVD grade)
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Brochure - Cited Antibodies

Brochure - Cited Antibodies

Download the latest version of GeneTex's Cited Antibodies brochure.
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New Therapeutic Paradigm for Cancers with Activated NRF2

New Therapeutic Paradigm for Cancers with Activated NRF2

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Download the latest version of GeneTex's Cancer flyer.
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GeneTex Launches Novel Recombinant RAS (G12D Mutant) Antibody [HL10]

GeneTex Launches Novel Recombinant RAS (G12D Mutant) Antibody [HL10]

GeneTex's RAS (G12D mutant) recombinant antibody is suitable for IHC staining and WB.
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Download the latest version of GeneTex's Zika Virus Research flyer.

Flyer-Zika Virus Research

Download the latest version of GeneTex's Zika Virus Research flyer.
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Cited Antibodies

Flyer - Cited Antibodies

Download the latest version of GeneTex's cited antibodies flyer.
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A Cancer Immunotherapy Holy Grail?
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Brochure - World Class Validated Antibodies

Download the latest version of GeneTex's World Class Validated Antibodies brochure.
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Poster - Cancer Signaling

Download the latest version of GeneTex's cancer signaling poster
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Pamphlet - Antibodies for Cancer Research

Download the latest version of GeneTex's pamphlet of antibodies for cancer research
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Metabolic Pathways

Flyer - Metabolic Pathways

Download the latest version of GeneTex's metabolic pathways flyer.
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Flyer - RNA-binding Proteins

Download the latest version of GeneTex's RNA-binding proteins flyer.
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Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.
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Cancer Immune Checkpoint

Flyer - Cancer Immune Checkpoints

Download the latest version of GeneTex's cancer immune checkpoint flyer
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Flyer - EGFR Signaling

Download the latest version of GeneTex's EGFR signaling flyer.
Literature
Brochure - Cited Antibodies

Brochure - Cited Antibodies

Download the latest version of GeneTex's Cited Antibodies brochure.
Literature

Flyer-Cancer

Download the latest version of GeneTex's Cancer flyer.
Literature
Download the latest version of GeneTex's Zika Virus Research flyer.

Flyer-Zika Virus Research

Download the latest version of GeneTex's Zika Virus Research flyer.
Literature
Cited Antibodies

Flyer - Cited Antibodies

Download the latest version of GeneTex's cited antibodies flyer.
Literature
World Class Validated Antibodies

Brochure - World Class Validated Antibodies

Download the latest version of GeneTex's World Class Validated Antibodies brochure.
Literature
Cancer Signaling

Poster - Cancer Signaling

Download the latest version of GeneTex's cancer signaling poster
Literature
Antibodies for Cancer Research

Pamphlet - Antibodies for Cancer Research

Download the latest version of GeneTex's pamphlet of antibodies for cancer research
Literature
Metabolic Pathways

Flyer - Metabolic Pathways

Download the latest version of GeneTex's metabolic pathways flyer.
Literature

Flyer - RNA-binding Proteins

Download the latest version of GeneTex's RNA-binding proteins flyer.
Literature

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.
Literature
Cancer Immune Checkpoint

Flyer - Cancer Immune Checkpoints

Download the latest version of GeneTex's cancer immune checkpoint flyer
Newsletter
Article Alert: IFNγ-stimulated KAT8-IRF1 Condensates Activate PD-L1 Expression and Promote Immune Evasion

IFNγ-stimulated KAT8-IRF1 Condensates Activate PD-L1 Expression and Promote Immune Evasion

Newsletter
PARPs as Therapeutic Targets in Clinical Oncology

PARPs as Therapeutic Targets in Clinical Oncology

Newsletter
HCK Inhibition: Boosting Immunotherapy’s Efficacy and Utility?

HCK Inhibition: Boosting Immunotherapy’s Efficacy and Utility?

Newsletter
Article Alert: C3aR and TNF-αR Antagonists as Potential Therapies for Medulloblastoma

Article Alert: C3aR and TNF-αR Antagonists as Potential Therapies for Medulloblastoma

Newsletter
ADAM17: A Major “Sheddase” in Human Disease

ADAM17: A Major “Sheddase” in Human Disease

ADAM17: A Major “Sheddase” in Human Disease
Newsletter
Carbonic Anhydrase IX (CA IX): Acid-Base Regulator and Driver of Tumorigenesis

Carbonic Anhydrase IX (CA IX): Acid-Base Regulator and Driver of Tumorigenesis

Carbonic anhydrase IX (CA IX) is a transmembrane, hypoxia-induced zinc metalloenzyme that converts carbon dioxide to bicarbonate and protons...
Newsletter

A Rising StAR in Cancer Research

Steroidogenic acute regulatory protein 1 (StAR/StARD1) mediates the rate-limiting step in steroidogenesis...
Newsletter

NEK7: An Essential Regulator of NLRP3 Inflammasome Activation

NEK7: An Essential Regulator of NLRP3 Inflammasome Activation
Newsletter
Nuclear PD-L1 Mediates Pyroptosis in Cancer Cells

Nuclear PD-L1 Mediates Pyroptosis in Cancer Cells

Nuclear PD-L1 Mediates Pyroptosis in Cancer Cells
Newsletter

Lateral Flow Assay for Influenza & SARS-CoV-2 Viruses Detection

Influenza A & B Virus Antibodies (IVD grade)
Newsletter
New Therapeutic Paradigm for Cancers with Activated NRF2

New Therapeutic Paradigm for Cancers with Activated NRF2

New Therapeutic Paradigm for Cancers with Activated NRF2
Newsletter
GeneTex Launches Novel Recombinant RAS (G12D Mutant) Antibody [HL10]

GeneTex Launches Novel Recombinant RAS (G12D Mutant) Antibody [HL10]

GeneTex's RAS (G12D mutant) recombinant antibody is suitable for IHC staining and WB.
Newsletter

A Cancer Immunotherapy Holy Grail?

A Cancer Immunotherapy Holy Grail?