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Oncoproteins

Oncoproteins

Oncoproteins

The products of metazoan cell proto-oncogenes are generally key constituents of the cell signaling and gene expression machinery that regulate cell growth and proliferation. When mutated, amplified, or otherwise expressed in a dysregulated manner, these genes can become cellular oncogenes and their oncoprotein products drive tumorigenic cell growth. Examples of proto-oncogenes include the RAS genes, ERBB2, MYC, and ABL1. Certain viruses, or oncoviruses, have the capability to cause cancers through the action of viral genome-encoded oncoproteins that target metazoan cell factors or pathways.
Highlighted Products
Citation Support  KOKD Validation  Comparable Abs  IP/MS Analysis  Orthogonal Validation  Protein Overexpression

 

AKT antibody [N3C2], Internal

AKT antibody
(GTX121937)
Ras antibody

Ras antibody
(GTX132480)
Aurora B antibody

Aurora B antibody
(GTX130211)

 

VEGF antibody

VEGF antibody
(GTX102643)
EGFR antibody [N1-2], N-term

EGFR antibody
(GTX121919)
Phospho-EGF Receptor (Tyr1068) antibody

Phospho-EGF Receptor (Tyr1068) antibody
(GTX132810)
Her2 / ErbB2 antibody [C2C3], C-term

Her2 / ErbB2 antibody
(GTX100509)
Her2 / ErbB2 (phospho Tyr1221/Tyr1222) antibody

Her2 / ErbB2 (phospho Tyr1221/Tyr1222) antibody
(GTX133445)
PDGF Receptor beta (phospho Tyr751) antibody

PDGF Receptor beta (phospho Tyr751) antibody
(GTX133525)
Newsletter
GeneTex Launches Novel Recombinant RAS (G12D Mutant) Antibody [HL10]

GeneTex Launches Novel Recombinant RAS (G12D Mutant) Antibody [HL10]

GeneTex's RAS (G12D mutant) recombinant antibody is suitable for IHC staining and WB.
Newsletter

A Cancer Immunotherapy Holy Grail?

A Cancer Immunotherapy Holy Grail?
Literature
World Class Validated Antibodies

Brochure - World Class Validated Antibodies

Download the latest version of GeneTex's World Class Validated Antibodies brochure.
Pathways

Wnt Pathway

Wnt proteins are secreted morphogens that are required for various developmental processes.
Literature
Cancer Signaling

Poster - Cancer Signaling

Download the latest version of GeneTex's cancer signaling poster
Literature

Flyer - EGFR Signaling

Download the latest version of GeneTex's EGFR signaling flyer.
Literature

Flyer - RNA-binding Proteins

Download the latest version of GeneTex's RNA-binding proteins flyer.
Literature

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.
Literature
Antibodies for Cancer Research

Pamphlet - Antibodies for Cancer Research

Download the latest version of GeneTex's pamphlet of antibodies for cancer research
Literature
World Class Validated Antibodies

Brochure - World Class Validated Antibodies

Download the latest version of GeneTex's World Class Validated Antibodies brochure.
Literature
Cancer Signaling

Poster - Cancer Signaling

Download the latest version of GeneTex's cancer signaling poster
Literature

Flyer - EGFR Signaling

Download the latest version of GeneTex's EGFR signaling flyer.
Literature

Flyer - RNA-binding Proteins

Download the latest version of GeneTex's RNA-binding proteins flyer.
Literature

Pamphlet - Hot Products

Download the latest version of GeneTex's pamphlet of hot products.
Literature
Antibodies for Cancer Research

Pamphlet - Antibodies for Cancer Research

Download the latest version of GeneTex's pamphlet of antibodies for cancer research