Stem cells are usually defined functionally by their ability to proliferate for an extended time and to differentiate from unspecialized cells into specific cell types. In addition, stem cell populations are identified by the expression, or lack of expression, of various markers. Listed below are antibodies from GeneTex’s stem cell catalog that are valuable tools for the characterization and isolation of stem cells. The tables list representative markers for embryonic, neural, hematopoietic, and mesenchymal stem cell populations and appropriate reagents to detect these factors (1,2).

 

Common Stem Cell Markers

Marker

Antibody

Oct4 (POU5F1)

GTX627419

Nanog

GTX627421

Sox2

GTX627404

SSEA-4

GTX48037

CD30

GTX01872

GATA4

GTX113194

CD133

GTX100567

  

Neural Stem Cell Markers

Marker

Antibody

Vimentin

GTX629744

NeuroD1

GTX134069

MAP2

GTX133109

Tau

GTX130462

Synaptophysin

GTX633972

OTX2

GTX133210

GFAP

GTX108711

 

Hematopoietic Stem Cell Markers

Marker

Antibody

CD31

GTX130274

CD34

GTX28158

FLI1

GTX112937

FLK1

GTX129943

CD4

GTX44531

CD8

GTX74773

GATA1

GTX01159

 

Mesenchymal Stem Cell Markers

Marker

Antibody

CD73

GTX113509

CD90 / Thy1

GTX130072

CD105

GTX112685

Fibronectin

GTX112794

N-Cadherin

GTX127345

References:

Stem Cell Res. 2018 Jan;26:36-43.
Stem Cell Information. Bethesda, MD: NIH