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AIPL1 antibody

Anti-AIPL1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55497
Anti-AIPL1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55497
Anti-AIPL1 antibody used in Western Blot (WB). GTX55497

Cat. No. GTX55497

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF

Reactivity

Human, Mouse
Package
100 μl ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:100
Not tested in other applications.

Calculated MW

44 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-384 of human AIPL1 (NP_055151.3).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

aryl hydrocarbon receptor interacting protein like 1 , AIPL2 , LCA4

Cellular Localization

Cytoplasm,Nucleus

Background

Leber congenital amaurosis (LCA) is the most severe inherited retinopathy with the earliest age of onset and accounts for at least 5% of all inherited retinal diseases. Affected individuals are diagnosed at birth or in the first few months of life with nystagmus, severely impaired vision or blindness and an abnormal or flat electroretinogram. The photoreceptor/pineal-expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, is located within the LCA4 candidate region. The encoded protein contains three tetratricopeptide motifs, consistent with chaperone or nuclear transport activity. Mutations in this gene may cause approximately 20% of recessive LCA. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Database

Research Area

DATA IMAGES

Anti-AIPL1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55497

GTX55497 ICC/IF Image

ICC/IF analysis of Y79 cells using GTX55497 AIPL1 antibody.
Blue : DAPI
Dilution : 1:100

Anti-AIPL1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55497

GTX55497 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX55497 AIPL1 antibody.
Blue : DAPI

Anti-AIPL1 antibody used in Western Blot (WB). GTX55497

GTX55497 WB Image

WB analysis of various sample lysates using GTX55497 AIPL1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399