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APBA1 antibody

Anti-APBA1 antibody used in IHC (Paraffin sections) (IHC-P). GTX17173
Anti-APBA1 antibody used in Western Blot (WB). GTX17173

Cat. No. GTX17173

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, ELISA

Reactivity

Human, Mouse, Rat
Package
100 μg ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5 μg/mL
IHC-P 20 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

93 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , Rat Brain Tissue Lysate(GTX27942)

Product Note

At least two alternatively spliced isoforms are known to exist; this antibody will detect both isoforms. This antibody is predicted to not cross-react with other APBA proteins.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

APBA1 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human APBA1.The immunogen is located within amino acids 90 - 140 of APBA1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

amyloid beta precursor protein binding family A member 1 , D9S411E , LIN10 , MINT1 , X11 , X11A , X11ALPHA

Cellular Localization

Cytoplasm,Nucleus

Background

The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-APBA1 antibody used in IHC (Paraffin sections) (IHC-P). GTX17173

GTX17173 IHC-P Image

IHC-P analysis of human brain tissue using GTX17173 APBA1 antibody.
Working concentration : 20 μg/ml

Anti-APBA1 antibody used in Western Blot (WB). GTX17173

GTX17173 WB Image

WB analysis of rat brain tissue lysate in (A) the absence and (B) the presence of blocking peptide using GTX17173 APBA1 antibody.
Working concentration : 0.5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399