APOBEC3C antibody

Name: APOBEC3C antibody
Brand: GeneTex
SKU: GTX102164
Price: 399.00 USD
Rating: 4 (1 reviews)

Anti-APOBEC3C antibody used in Western Blot (WB). GTX102164

Cat. No. GTX102164

Reference 7

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IP
Reactivity	Human
Package	100 μl ($399), 25 μl ($169)

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View product citations for antibody GTX102164 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:500-1:3000
IP	Assay dependent

Not tested in other applications.

Calculated MW

23 kDa. ( Note )

Positive Control

NCI-H929

Product Note

Knockdown/Knockout validation was supported by references (PMID: 31448067)

Predict Reactivity

Chimpanzee, Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human APOBEC3C. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2616091

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

apolipoprotein B mRNA editing enzyme catalytic subunit 3C , A3C , APOBEC1L , ARDC2 , ARDC4 , ARP5 , PBI , bK150C2.3

Background

This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. [provided by RefSeq]

Database

Gene ID: 27350 APOBEC3C
UniProt: Q9NRW3 APOBEC3C

Research Area

DATA IMAGES

GTX102164 WB Image

Sample (30 ug of whole cell lysate)
A: NCI-H929
12% SDS PAGE
GTX102164 diluted at 1:2000

GTX102164 WB Image

The data was published in the journal Oncogenesis in 2018. PMID: 30467308

REFERENCE

Application Reference

Constantin D et al. FEBS J 2021; (Epub) APOBEC3C, a nucleolar protein induced by genotoxins, is excluded from DNA damage sites.

Application : WB

Reactivity : Human

Kawamura Y et al. J Extracell Vesicles 2019; 8 (1) : 1643214 Extracellular vesicles mediate the horizontal transfer of an active LINE-1 retrotransposon.

Application : WB

Reactivity : Human

Michalski D et al. J Biol Chem 2019; Zika virus noncoding sfRNAs sequester multiple host-derived RNA-binding proteins and modulate mRNA decay and splicing during infection.

Application : WB

Reactivity : Human

Yumi Kawamura et al. Journal of Extracellular Vesicles 2019; 8 (1) Extracellular vesicles mediate the horizontal transfer of an active LINE-1 retrotransposon.

Application : WB

Reactivity : Human

Kim GC et al. Oncogenesis 2018; 7 (11) : 91 Upregulation of Ets1 expression by NFATc2 and NFKB1/RELA promotes breast cancer cell invasiveness.

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