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APRIL antibody

Anti-APRIL antibody used in IHC (Paraffin sections) (IHC-P). GTX31268
Anti-APRIL antibody used in Western Blot (WB). GTX31268

Cat. No. GTX31268

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, ELISA

Reactivity

Human, Mouse
Package
100 μg ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 4 μg/mL
IHC-P 10 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

27 kDa. ( Note )

Positive Control

Jurkat Cell Lysate(GTX27899) , Human Prostate Tissue Lysate(GTX29184)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

APRIL antibody was raised against a synthetic peptide corresponding to amino acids within a extracellular domain of human APRIL.The immunogen is located within amino acids 180 - 230 of APRIL.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TNF superfamily member 13 , APRIL , CD256 , TALL-2 , TALL2 , TNLG7B , TRDL-1 , UNQ383/PRO715 , ZTNF2

Cellular Localization

Secreted

Background

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]

Database

Research Area

DATA IMAGES

Anti-APRIL antibody used in IHC (Paraffin sections) (IHC-P). GTX31268

GTX31268 IHC-P Image

IHC-P analysis of human prostate tissue using GTX31268 APRIL antibody.
Working concentration : 10 μg/ml

Anti-APRIL antibody used in Western Blot (WB). GTX31268

GTX31268 WB Image

WB analysis of Jurkat cell lysate using GTX31268 APRIL antibody.
Working concentration : 1 μg/ml (A), 2 μg/ml (B), and 4 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399