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Acetyl-CoA Carboxylase 1 antibody

Anti-Acetyl-CoA Carboxylase 1 antibody used in Western Blot (WB). GTX52372

Cat. No. GTX52372

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all Acetyl-CoA Carboxylase 1 products

APPLICATION

Application Note

WB 1:500-1:2000, IHC 1:50-1:200

Calculated MW

266 kDa. ( Note )

Product Note

ACACA

PROPERTIES

Form

Liquid

Buffer

PBS, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human Acetyl-CoA Carboxylase 1

Purification

Antigen affinity purification

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

acetyl-CoA carboxylase alpha , ACAC , ACACAD , ACC , ACC1 , ACCA

Cellular Localization

Cytoplasm

Background

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

  • Gene ID: 31 ACACA
  • UniProt: Q13085 ACACA

Research Area

DATA IMAGES

Anti-Acetyl-CoA Carboxylase 1 antibody used in Western Blot (WB). GTX52372

GTX52372 WB Image

Western blot analysis of ACC1 expression in PMA treated NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399