APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:100 - 1:1000 |
| Assay dependent |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
200 μg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant hu-ALK2 extra cellular domain
Purification
Protein G purified
From tissue culture supernatant
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
ACTRI , ACVR1 , ACVR1A , ACVRLK2 , ALK2 , FOP , SKR1 , TSRI , activin A receptor type 1 , Activin A receptor type I , Activin Receptor type IA
Cellular Localization
Membrane
Background
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
![Anti-Activin Receptor Type IA antibody [9J17] used in IHC (Paraffin sections) (IHC-P). GTX52503](/templates/default/js/lightbox/images/loading.gif "Anti-Activin Receptor Type IA antibody [9J17] used in IHC (Paraffin sections) (IHC-P). GTX52503")
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GTX52503 IHC-P Image
IHC-P analysis of formalin fixed human placenta tissue using GTX52503 Activin Receptor Type IA antibody [9J17].
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REFERENCE
There are currently no references for Activin Receptor Type IA antibody [9J17] (GTX52503). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Activin Receptor Type IA antibody [9J17] (GTX52503). Be the first to share your experience with this product.
![Anti-Activin Receptor Type IA antibody [9J17] used in IHC (Paraffin sections) (IHC-P). GTX52503](/upload/website/prouct_img/small/GTX52503/GTX52503_20191119_IHC-P_w_23060900_750.webp "Anti-Activin Receptor Type IA antibody [9J17] used in IHC (Paraffin sections) (IHC-P). GTX52503")
![Anti-Activin Receptor Type IA antibody [9J17] used in IHC (Paraffin sections) (IHC-P). GTX52503](/upload/website/prouct_img/normal/GTX52503/GTX52503_20191119_IHC-P_w_23060900_750.webp "Anti-Activin Receptor Type IA antibody [9J17] used in IHC (Paraffin sections) (IHC-P). GTX52503")