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BCL6 antibody [PG-B6]

Anti-BCL6 antibody [PG-B6] used in IHC (Paraffin sections) (IHC-P). GTX03321

Cat. No. GTX03321

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 PG-B6

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($469)
See all BCL6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:50-1:100

Note :

IHC-P
Pretreatment : EDTA Buffer pH 8.0 for 30 min at RT
Not tested in other applications.

Calculated MW

79 kDa. ( Note )

Positive Control

Tonsil

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Antigen Species

Human

Immunogen

Recombinant BCL6 protein corresponding to amino acids 3-484 of the human BCL6 protein

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BCL6 transcription repressor , BCL5 , BCL6A , LAZ3 , ZBTB27 , ZNF51

Cellular Localization

Nucleus

Background

The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]

Database

Research Area

DATA IMAGES

Anti-BCL6 antibody [PG-B6] used in IHC (Paraffin sections) (IHC-P). GTX03321

GTX03321 IHC-P Image

IHC-P analysis of human tonsil tissue section using GTX03321 BCL6 antibody [PG-B6].

REFERENCE

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REVIEW

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Package List Price ($)
$ 469