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BCOR antibody [C-10]

Cat. No. GTX01587

Reference 3

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 C-10

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($399)
See all BCOR products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100

Note :

IHC-P
Pretreatment of deparaffinized tissue with heat-induced epitope retrieval or enzymatic retrieval is recommended.
Not tested in other applications.

Calculated MW

192 kDa. ( Note )

Positive Control

Endometrial stromal sarcoma

PROPERTIES

Form

Liquid

Buffer

Tris-HCl buffer, 0.2% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptideagainst amino acid 1-300 mapping at the N-terminus of BCOR of human origin

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BCL6 corepressor , ANOP2 , MAA2 , MCOPS2

Cellular Localization

Nucleus

Background

The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.[provided by RefSeq, Jun 2010]

Database

Research Area

REFERENCE

Clone Reference

2020; High-grade neuroepithelial tumor with BCOR exon 15 internal tandem duplication-a comprehensive clinical, radiographic, pathologic, and genomic analysis
Application : IHC-P
Reactivity : Human
2020; BCOR Expression in Mullerian Adenosarcoma: A Potential Diagnostic Pitfall
Application : IHC-P
Reactivity : Human
2019; Undifferentiated Uterine Sarcomas Represent Under-Recognized High-grade Endometrial Stromal Sarcomas
Application : IHC-P
Reactivity : Human
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REVIEW

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Package List Price ($)
$ 399