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BRD2 antibody

Anti-BRD2 antibody used in Western Blot (WB). GTX19276

Cat. No. GTX19276

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μg ($629)
See all BRD2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.025 - 0.1 μg/ml
Not tested in other applications.

Calculated MW

88 kDa. ( Note )

Product Note

The specific epitope is in the region between aa 550 and 600 of human BRD2.

Predict Reactivity

Bovine, Gorilla, Rhesus Monkey, Northern white-cheeked gibbon, crab-eating macaque, White-tufted-ear marmoset(>80% identity)

PROPERTIES

Form

Liquid

Buffer

Tris-Citrate/Phosphate

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Immunogen

Synthetic peptide representing a portion of the protein between the putative nuclear localization signal and the ET domain.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BRD2 , D6S113E , FSH , FSRG1 , NAT , O27.1.1 , RING3 , RNF3 , bromodomain containing 2

Cellular Localization

Nucleus

Background

This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]

Database

Research Area

DATA IMAGES

Anti-BRD2 antibody used in Western Blot (WB). GTX19276

GTX19276 WB Image

WB analysis of extract (10ug) of HeLa cells untreated (-) or treated (+) with calf intestinal phosphatase using GTX19276 BRD2 antibody.
Dilution : 0.05μg/ml

REFERENCE

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REVIEW

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Package List Price ($)
$ 629