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BUB1 antibody [14H5]

Cat. No. GTX80316

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 14H5

Isotype

 IgG1

Application

 ICC/IF, IP

Reactivity

 Human
Package
50 μl ($399)
See all BUB1 products

APPLICATION

Application Note

Recommended Starting Dilutions:
Use at 1μg/ml
Optimal dilutions should be determined experimentally by the researcher.

Calculated MW

122 kDa. ( Note )

Product Note

Human BUB1. Not tested for reactivity with rodents or other vertebrates

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human BUB1/CFA

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BUB1 mitotic checkpoint serine/threonine kinase , BUB1A , BUB1L , hBUB1

Cellular Localization

Nucleus

Background

This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399