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C-Peptide antibody [C-PEP-01] (Biotin)

Anti-C-Peptide antibody [C-PEP-01] (Biotin) used in IHC (Paraffin sections) (IHC-P). GTX80204

Cat. No. GTX80204

Host

Mouse

Clonality

Monoclonal

Clone Name

C-PEP-01

Isotype

IgG1

Application

ICC/IF, IHC-P, ELISA, RIA

Reactivity

Human
Package
100 μg ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC-P Assay dependent
ELISA Assay dependent
RIA Assay dependent
Not tested in other applications.

Calculated MW

12 kDa. ( Note )

Product Note

This antibody reacts specifically with C-peptide, a part of the Proinsulin molecule. No cross-reactivity with Insulin or other peptide hormones or proteins was observed.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human C-peptide conjugated to bovine serum albumin.

Purification

Purified IgG

Conjugation

Biotin
The reagent is free of unconjugated biotin.

RRID

AB_11172675

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

insulin , IDDM , IDDM1 , IDDM2 , ILPR , IRDN , MODY10

Cellular Localization

Secreted

Background

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

Database

Research Area

DATA IMAGES

Anti-C-Peptide antibody [C-PEP-01] (Biotin) used in IHC (Paraffin sections) (IHC-P). GTX80204

GTX80204 IHC-P Image

Immunohistochemistry staining of human pancreas (paraffin-embedded sections) with anti-human to C-peptide of Proinsulin (C-PEP-01).

REFERENCE

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399