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C-Peptide antibody [C-PEP-01]

Anti-C-Peptide antibody [C-PEP-01] used in IHC (Paraffin sections) (IHC-P). GTX27761

Cat. No. GTX27761

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 C-PEP-01

Isotype

 IgG1

Application

 ICC/IF, IHC-P, ELISA, RIA

Reactivity

 Human
Package
100 μg ($399)
See all C-Peptide products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC-P Assay dependent
ELISA Assay dependent
RIA Assay dependent
Not tested in other applications.

Calculated MW

12 kDa. ( Note )

Product Note

This antibody reacts specifically with C-peptide, No cross-reactivity with Insulin or other peptide hormones or proteins was observed.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human C-peptide conjugated to bovine serum albumin.

Purification

Purified by precipitation and chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

insulin , IDDM , IDDM1 , IDDM2 , ILPR , IRDN , MODY10

Cellular Localization

Secreted

Background

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

Database

Research Area

DATA IMAGES

Anti-C-Peptide antibody [C-PEP-01] used in IHC (Paraffin sections) (IHC-P). GTX27761

GTX27761 IHC-P Image

IHC-P analysis of human pancreas tissue using GTX27761 C-Peptide antibody [C-PEP-01].

REFERENCE

Clone Reference

Mihara Y et al. J Tissue Eng Regen Med 2017; (Epub) Production of pancreatic progenitor cells from human induced pluripotent stem cells using a three-dimensional suspension bioreactor system.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399