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C3 / C3a antibody

Anti-C3 / C3a antibody used in Western Blot (WB). GTX78198

Cat. No. GTX78198

Host

 Chicken

Clonality

 Polyclonal

Isotype

 IgY

Application

 WB, ELISA

Reactivity

 Human
Package
100 μg ($399)
See all C3 products

APPLICATION

Application Note

This product can be used at 1:2,000 to 1:10,000 for both ELISA and immunoblot testing. User needs to try out the titrations for optimization in assay.

Calculated MW

187 kDa. ( Note )

Product Note

Binds to a stong band at about 97KDa (C3a), two weaker bands with one at about 115KDa (C3 alpha) and the other at 36-50KDa.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human C3 alpha peptide aa 678-692

Purification

Affinity purified with antigen

Conjugation

Unconjugated

RRID

AB_625855

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

complement C3 , AHUS5 , ARMD9 , ASP , C3a , C3b , CPAMD1 , HEL-S-62p

Cellular Localization

Secreted

Background

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]

Database

Research Area

DATA IMAGES

Anti-C3 / C3a antibody used in Western Blot (WB). GTX78198

GTX78198 WB Image

Western Blot analysis of GTX78198 chicken anti-human C3a on human serum (1 ul).

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399