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C8orf4 antibody

Anti-C8orf4 antibody used in IHC (Paraffin sections) (IHC-P). GTX64775
Anti-C8orf4 antibody used in IHC (Paraffin sections) (IHC-P). GTX64775
Anti-C8orf4 antibody used in IHC (Paraffin sections) (IHC-P). GTX64775

Cat. No. GTX64775

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all C8orf4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

12 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-106 of human C8orf4 (NP_064515.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transcriptional and immune response regulator , C8orf4 , TC-1 , TC1

Cellular Localization

Cytoplasm,Nucleus speckle,Nucleus,Nucleolus

Background

This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. [provided by RefSeq, Nov 2011]

Database

Research Area

DATA IMAGES

Anti-C8orf4 antibody used in IHC (Paraffin sections) (IHC-P). GTX64775

GTX64775 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX64775 C8orf4 antibody.
Dilution : 1:100

Anti-C8orf4 antibody used in IHC (Paraffin sections) (IHC-P). GTX64775

GTX64775 IHC-P Image

IHC-P analysis of human stomach tissue using GTX64775 C8orf4 antibody.
Dilution : 1:100

Anti-C8orf4 antibody used in IHC (Paraffin sections) (IHC-P). GTX64775

GTX64775 IHC-P Image

IHC-P analysis of rat lung tissue using GTX64775 C8orf4 antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399