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CAPS2 antibody

Anti-CAPS2 antibody used in IHC (Paraffin sections) (IHC-P). GTX85405
Anti-CAPS2 antibody used in IHC (Paraffin sections) (IHC-P). GTX85405
Anti-CAPS2 antibody used in Western Blot (WB). GTX85405

Cat. No. GTX85405

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all CAPS2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5 - 1 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

148 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , Human Brain Tissue Lysate(GTX27918)

Product Note

Multiple isoforms of CAPS2 are known to exist. This CAPS2 antibody is predicted to be specific to CAPS2 and not recognize CAPS1.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CAPS2 antibody was raised against a 19 amino acid synthetic peptide near the center of the human CAPS2.The immunogen is located within amino acids 510 - 560 of CAPS2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

calcium dependent secretion activator 2 , CAPS2

Cellular Localization

Cell junction, synapse

Background

CAPS2 and the related protein CAPS1 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles; CAPS-deficient neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. Like CAPS1, numerous isoforms of CAPS2 are known to exist. These isoforms show distinct expression patterns in the brain. For example, CAPS2b showed high expression in the developing cerebellum. Furthermore, one version of CAPS2 mRNA that lacks exon 3 is detected in some autistic patients, suggesting that the differential expression pattern of CAPS2 is involved in neuronal development. This CAPS2 antibody is predicted to be specific to CAPS2 and not recognize CAPS1.

Database

Research Area

DATA IMAGES

Anti-CAPS2 antibody used in IHC (Paraffin sections) (IHC-P). GTX85405

GTX85405 IHC-P Image

IHC-P analysis of human brain tissue using GTX85405 CAPS2 antibody.
Working concentration : 20 μg/ml

Anti-CAPS2 antibody used in IHC (Paraffin sections) (IHC-P). GTX85405

GTX85405 IHC-P Image

IHC-P analysis of human brain tissue using GTX85405 CAPS2 antibody.
Working concentration : 5 μg/ml

Anti-CAPS2 antibody used in Western Blot (WB). GTX85405

GTX85405 WB Image

WB analysis of human brain tissue lysate using GTX85405 CAPS2 antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399