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CARD10 antibody

Anti-CARD10 antibody used in IHC (Paraffin sections) (IHC-P). GTX31678

Cat. No. GTX31678

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P, ELISA

Reactivity

 Human
Package
100 μg ($399)
See all CARD10 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

116 kDa. ( Note )

Positive Control

Human Kidney Tissue Slide

Product Note

This antibody is human specific. At least three isoforms are known to exist; this antibody will only detect isoform 1. This antibody is predicted not to cross-react with other CARMA proteins.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CARD10 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human CARD10.The immunogen is located within the first 50 amino acids of CARD10.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

caspase recruitment domain family member 10 , BIMP1 , CARMA3

Cellular Localization

Cytoplasm

Background

The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM, Mar 2008]

Database

Research Area

DATA IMAGES

Anti-CARD10 antibody used in IHC (Paraffin sections) (IHC-P). GTX31678

GTX31678 IHC-P Image

IHC-P analysis of human kidney tissue using GTX31678 CARD10 antibody.
Working concentration : 5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399