APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 11 - 44 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse, Rat, Rabbit, Bovine, Hamster, Monkey, Elephant, Gibbon, Gorilla, Marmoset, Panda(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 16 amino acid peptide from 2nd extracellular domain of human CCR10.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_370964
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
C-C motif chemokine receptor 10 , CC motif chemokine receptor 10 , CCR10 , GPR2
Cellular Localization
Cell membrane
Background
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008]
Database
Research Area
DATA IMAGES
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GTX71025 IHC-P Image
IHC-P analysis of brain, glioblastoma tissue using GTX71025 CCR10 antibody.
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GTX71025 IHC-P Image
IHC-P analysis of human colon, carcinoma tissue using GTX71025 CCR10 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX71025 IHC-P Image
IHC-P analysis of human thymus tissue using GTX71025 CCR10 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX71025 IHC-P Image
IHC-P analysis of brain, cortex, neurons tissue using GTX71025 CCR10 antibody.
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REFERENCE
There are currently no references for CCR10 antibody (GTX71025). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CCR10 antibody (GTX71025). Be the first to share your experience with this product.
