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CCR4 antibody

Anti-CCR4 antibody used in Immunohistochemistry (IHC). GTX21669

Cat. No. GTX21669

Reference 1

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, FACS, ELISA, IHC

Reactivity

 Human, Mouse, Monkey
Package
100 μg ($399)
See all CCR4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500
ICC/IF Assay dependent
IHC-P Assay dependent
FACS 1:12
ELISA 1:30,000
IHC 1:200
Not tested in other applications.

Calculated MW

41 kDa. ( Note )

Product Note

Peptide sequence is < 50 % identical to other human chemokine receptors in this region.

PROPERTIES

Form

Liquid

Buffer

10mM KHPO₄, 140mM NaCl, 0.1% BSA

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

17SNYYLYESIPKPCTKEGIKAFGE39 corresponding to human CCR4 extracellular domain

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CC motif chemokine receptor 4,CCCKR4,CCR4,CD194,CKR4,CMKBR4,ChemR13,HGCN:14099,K55,C-C motif chemokine receptor 4

Cellular Localization

Cell membrane

Background

The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CCR4 antibody used in Immunohistochemistry (IHC). GTX21669

GTX21669 IHC Image

IHC analysis of human spleen tissue using GTX21669 CCR4 antibody.

REFERENCE

Application Reference

S Li et al. J Cancer 2024; 15 (3) : 632-644 Exploring Prognostic Immune Microenvironment-Related Genes in Head and Neck Squamous Cell Carcinoma from the TCGA Database
Application : IHC-P
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Package List Price ($)
$ 399