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CCR6 antibody

Anti-CCR6 antibody used in Immunohistochemistry (IHC). GTX21659

Cat. No. GTX21659

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, FACS, ELISA, IHC

Reactivity

 Human
Package
100 μg ($399)
See all CCR6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:250
FACS 2-6μl/10⁶cells/50-100μl
ELISA 1:37,500
IHC 1:125
Not tested in other applications.

Calculated MW

42 kDa. ( Note )

Product Note

Peptide sequence is <50% identical to other human chemokine receptors in this region.

PROPERTIES

Form

Liquid

Buffer

10mM KHPO₄, 140mM NaCl, 0.1% BSA

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide YFVSVNTSYYSVDSEMLLCSLQEVRQFSR to amino acid residues 18 - 46 of human CCR6

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BN1,CC CKR6,CC motif chemokine receptor 6,CCCKR6,CCR6,CD196,CKRL3,CMKBR6,DCR2,DRY6,GPR29,GPRCY4,STRL22,C-C motif chemokine receptor 6

Cellular Localization

Cell membrane,Cell surface

Background

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CCR6 antibody used in Immunohistochemistry (IHC). GTX21659

GTX21659 IHC Image

IHC analysis of human spleen tissue using GTX21659 CCR6 antibody.

REFERENCE

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REVIEW

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Package List Price ($)
$ 399