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CCXCR1 antibody

Anti-CCXCR1 antibody used in IHC (Paraffin sections) (IHC-P). GTX77973

Cat. No. GTX77973

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P, ELISA, IHC

Reactivity

 Human
Package
25 μg ($299)
See all CCXCR1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1 - 2 μg/ml
ELISA Assay dependent
IHC Assay dependent
Not tested in other applications.

Calculated MW

39 kDa. ( Note )

Predict Reactivity

Bovine, Monkey, Gibbon, Gorilla, Marmoset, Panda(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 20 amino acid peptide from 2nd extracellular domain of human XCR1.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_424921

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

X-C motif chemokine receptor 1 , CCXCR1 , GPR5 , XC motif chemokine receptor 1 , XCR1

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CCXCR1 antibody used in IHC (Paraffin sections) (IHC-P). GTX77973

GTX77973 IHC-P Image

IHC-P analysis of human spleen tissue using GTX77973 CCXCR1 antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

Application Reference

Yamashita Y et al. Am J Clin Pathol 2011; 135 (4) : 556-64 XCR1 expression and biased VH gene usage are distinct features of diffuse large B-cell lymphoma initially manifesting in the bone marrow.
Application : IHC
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 299