APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500 - 1:2000 |
| 1:50 - 1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 52-352 of human MME (NP_009220.2).
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
membrane metalloendopeptidase , CALLA , CD10 , CMT2T , NEP , SCA43 , SFE
Cellular Localization
Cell membrane; Single-pass type II membrane protein
Background
The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. [provided by RefSeq, Aug 2017]
Database
Research Area
DATA IMAGES
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GTX32493 IHC-P Image
IHC-P analysis of human placenta tissue using GTX32493 CD10 antibody.
Dilution : 1:100
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GTX32493 IHC-P Image
IHC-P analysis of mouse kidney tissue using GTX32493 CD10 antibody.
Dilution : 1:100
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GTX32493 IHC-P Image
IHC-P analysis of human placenta tissue using GTX32493 CD10 antibody.
Blue : DAPI
Dilution : 1:100
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GTX32493 WB Image
WB analysis of various sample lysates using GTX32493 CD10 antibody.
Dilution : 1:1000
Loading : 25μg per lane
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GTX32493 IHC-P Image
IHC-P analysis of rat testis tissue using GTX32493 CD10 antibody.
Dilution : 1:100
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REFERENCE
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REVIEW
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