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CD105 antibody [MEM-229] (FITC)

Anti-CD105 antibody [MEM-229] (FITC) used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX79974

Cat. No. GTX79974

Reference 7

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MEM-229

Isotype

 IgG2a

Application

 ICC/IF, FACS

Reactivity

 Human, Pig
Package
100 test ($399)
See all CD105 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
FACS 20 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension
Not tested in other applications.

Calculated MW

71 kDa. ( Note )

Product Note

We do not recommend use of this product for Dog,Horse samples.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant Vaccinia virus containing the human CD105 (L-isoform) cDNA.

Purification

Purified by size-exclusion chromatography

Conjugation

Fluorescein isothiocyanate (FITC)

RRID

AB_11172034

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

END , ENG , HHT1 , ORW1 , endoglin , CD105

Cellular Localization

Cell membrane

Background

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]

Database

Research Area

DATA IMAGES

Anti-CD105 antibody [MEM-229] (FITC) used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX79974

GTX79974 ICC/IF Image

Immunofluorescence staining of an infarcted porcine heart with anti-CD105 (MEM-229; green; GTX79974); cell nuclei stained with DAPI (blue).

REFERENCE

Application Reference

Onate B et al. BMC Genomics 2013; 14 : 625 Stem cells isolated from adipose tissue of obese patients show changes in their transcriptomic profile that indicate loss in stemcellness and increased commitment to an adipocyte-like phenotype.
Application : FACS
Reactivity : Human

Clone Reference

Khatri M et al. J Cell Physiol 2017; (Epub) Therapeutic potential of porcine bronchoalveolar fluid-derived mesenchymal stromal cells in a pig model of LPS-induced ALI.
Khatri M et al. Stem Cell Res Ther 2015; 6:222 Porcine lung mesenchymal stromal cells possess differentiation and immunoregulatory properties.
Yang J et al. J Res Med Sci 2014; 19 (2):112-6 Adipose-derived stem cells from the breast.
Pei M et al. J Cell Physiol 2012; 227 (5):2163-74 Extracellular matrix deposited by synovium-derived stem cells delays replicative senescent chondrocyte dedifferentiation and enhances redifferentiation.
Application : FACS
Reactivity : Pig
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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399