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CD11b antibody [3V29]

Anti-CD11b antibody [3V29] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX52875

Cat. No. GTX52875

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 3V29

Isotype

 IgG1

Application

 ICC/IF, IHC-Fr, FACS

Reactivity

 Human
Package
100 μg ($399)
See all CD11b products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC-Fr 1:50 - 1:200
FACS 1:500 - 1:2000
Not tested in other applications.

Calculated MW

127 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The immunogen corresponding to a region within amino acids 17 - 1105 of human CD11b.

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD11B , CR3A , ITGAM , MAC1 , MAC1A , MO1A , SLEB6 , integrin subunit alpha M , CD11b , Mac-1 , Macrophage 1 antigen

Cellular Localization

Cell membrane,Membrane raft

Background

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Database

Research Area

DATA IMAGES

Anti-CD11b antibody [3V29] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX52875

GTX52875 ICC/IF Image

ICC/IF analysis of human microglial cells using GTX52875 CD11b antibody [3V29].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399