This antibody reacts with Kupffer cells and sinus lining cells on the liver. Skin Langerhans cells are always negative (Hogg et al. 1984).
PROPERTIES
Form
Liquid
Buffer
PBS, 1% BSA, 5% Sucrose
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Human Thymocytes followed by peripheral blood mononuclear cells.
Purification
Protein G purified
Conjugation
Phycoerythrin (PE)
RRID
AB_377297
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
CD14 molecule
Cellular Localization
Cell membrane , Secreted , Golgi apparatus
Background
The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Mar 2010]