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CD162 antibody [PSGL1/1601]

Anti-CD162 antibody [PSGL1/1601] used in IHC (Paraffin sections) (IHC-P). GTX34468
Anti-CD162 antibody [PSGL1/1601] used in IHC (Paraffin sections) (IHC-P). GTX34468

Cat. No. GTX34468

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 PSGL1/1601

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
100 μg ($529)
See all CD162 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1-2μg/ml for 30 minutes at RT

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human SELPLG (CD162) protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD162 , CLA , PSGL1 , SELPLG , selectin P ligand , PSGL-1

Cellular Localization

Membrane

Background

This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]

Database

Research Area

DATA IMAGES

Anti-CD162 antibody [PSGL1/1601] used in IHC (Paraffin sections) (IHC-P). GTX34468

GTX34468 IHC-P Image

IHC-P analysis of human spleen tissue using GTX34468 CD162 antibody [PSGL1/1601].

Anti-CD162 antibody [PSGL1/1601] used in IHC (Paraffin sections) (IHC-P). GTX34468

GTX34468 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX34468 CD162 antibody [PSGL1/1601].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529