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CD163 antibody [10D6]

Anti-CD163 antibody [10D6] used in IHC (Paraffin sections) (IHC-P). GTX01963

Cat. No. GTX01963

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 10D6

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($599)
See all CD163 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:200

Note :

IHC-P
The recommended fixative is 10% neutral-buffered formalin for paraffin-embedded tissue sections. Heat Induced Epitope Retreival (HIER) was performed in Epitope Retreival Solution pH6.
Not tested in other applications.

Calculated MW

125 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Prokaryotic recombinant protein corresponding to domains 1 to 4 of the N-terminal region of the CD163 molecule.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD163 molecule , M130 , MM130 , SCARI1

Background

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

Database

Research Area

DATA IMAGES

Anti-CD163 antibody [10D6] used in IHC (Paraffin sections) (IHC-P). GTX01963

GTX01963 IHC-P Image

IHC-P analysis of human placenta tissue using GTX01963 CD163 antibody [10D6]. Note cytoplasmic staining of Hofbauer cells.

REFERENCE

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REVIEW

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Package List Price ($)
$ 599