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CD18 antibody [MEM-48]

Cat. No. GTX78280

Host

Mouse

Clonality

Monoclonal

Clone Name

MEM-48

Isotype

IgG1

Application

FACS, IP, Blocking, Neutralizing/Inhibition

Reactivity

Human, Mouse
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS Assay dependent
IP Assay dependent
Blocking Assay dependent
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

85 kDa. ( Note )

Product Note

This antibody recognizes an epitope involving residues 534-546 in cysteine-rich repeat 3 of the CD18 antigen (Integrin beta2 chain).

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Leucocytes of a patient suffering from a LGL-type leukaemia.

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_625656

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD18 , ITGB2 , LAD , LCAMB , LFA1 , MAC1 , MF17 , MFI7 , integrin subunit beta 2 , Integrin beta2

Cellular Localization

Membrane

Background

This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Database

Research Area

REFERENCE

REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 339
Custom Conjugations