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CD1a antibody [O10]

Anti-CD1a antibody [O10] used in IHC (Paraffin sections) (IHC-P). GTX17186

Cat. No. GTX17186

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 O10

Isotype

 IgG1

Application

 IHC-P, IHC

Reactivity

 Human
Package
500 μl ($459)
See all CD1a products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:25‐1:50
IHC Assay dependent

Note :

IHC-P
Recommendations for antigen retrieval : EDTA buffer pH 8.0 at room temperature for 30 mins.
Not tested in other applications.

Calculated MW

37 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Antigen Species

Human

Immunogen

BALB/C mice were injected with thymus cells.

Purification

Unpurified

Conjugation

Unconjugated

RRID

AB_422618

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD1a molecule , CD1 , FCB6 , HTA1 , R4 , T6

Cellular Localization

Cell membrane , Endosome membrane

Background

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Database

Research Area

DATA IMAGES

Anti-CD1a antibody [O10] used in IHC (Paraffin sections) (IHC-P). GTX17186

GTX17186 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX17186 CD1a antibody [O10].

REFERENCE

Application Reference

Chandra N et al. AIDS Res Hum Retroviruses 2013; 29 (3) : 592-601 Depot medroxyprogesterone acetate increases immune cell numbers and activation markers in human vaginal mucosal tissues.
Application : IHC
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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 459