CD30 antibody [Ber-H2] (ready-to-use)

Name: CD30 antibody [Ber-H2] (ready-to-use)
Brand: GeneTex
SKU: GTX20871
Price: 399.00 USD
Rating: 5 (1 reviews)

Anti-CD30 antibody [Ber-H2] (ready-to-use) used in IHC (Paraffin sections) (IHC-P). GTX20871

Cat. No. GTX20871

Reference 1

Host	Mouse
Clonality	Monoclonal
Clone Name	Ber-H2
Isotype	IgG1
Application	IHC-P
Reactivity	Human
Package	6 ml ($399)

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View product citations for antibody GTX20871 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
IHC-P	Assay dependent
Note : IHC-P Recommendations for antigen retrieval : EDTA buffer pH 8.0 at room temperature for 30 mins.

Not tested in other applications.

Calculated MW

64 kDa. ( Note )

Product Note

This antibody recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. Its epitope is located between aa112-412.

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Antigen Species

Human

Immunogen

Co cell line established from a patient with Hodgkin's disease of T-cell lineage.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TNF receptor superfamily member 8 , CD30 , D1S166E , Ki-1

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Database

Gene ID: 943 TNFRSF8
UniProt: P28908 TNFRSF8

Research Area

DATA IMAGES

GTX20871 IHC-P Image

IHC-P analysis of human Hodgkin’s lymphoma tissue using GTX20871 CD30 antibody [Ber-H2] (ready-to-use).

REFERENCE

Clone Reference

Morimoto H et al. Biol Reprod 2012; 86 (5):148, 1-11 In vitro transformation of mouse testis cells by oncogene transfection.

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REVIEW