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CD4 antibody [YTS177]

Anti-CD4 antibody [YTS177] used in Western Blot (WB). GTX13846

Cat. No. GTX13846

Host

 Rat

Clonality

 Monoclonal

Clone Name

 YTS 177

Isotype

 IgG2a

Application

 WB, Neutralizing/Inhibition

Reactivity

 Mouse
Package
500 μg ($399)
See all CD4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
Neutralizing/Inhibition Assay dependent

Note :

Neutralizing/Inhibition
in vivo blockade of CD4+ T-cell responses
Not tested in other applications.

Calculated MW

51 kDa. ( Note )

Product Note

The YTS 177 antibody has been shown to compete with clones GK1.5 and YTS 191 for CD4 binding. The YTS 177 antibody has been reported to be non-depleting but binding does induce rapid internalization of CD4 on both CD4+ Foxp3- T cells and Foxp3+ regulatory T cells. Further, the YTS 177 clone has been shown to suppress or even prevent allograft rejection, allergic reactions and autoimmune responses.

PROPERTIES

Form

Liquid

Buffer

Filter-sterilized PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Mouse Spleen Cells

Purification

Protein G purified
From tissue culture supernatant

Purity

>95% (Determined by SDS-PAGE)

Endotoxin

< 0.002 EU/弮g (Determined by LAL assay)

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Cellular Localization

Cell membrane

Database

Research Area

DATA IMAGES

Anti-CD4 antibody [YTS177] used in Western Blot (WB). GTX13846

GTX13846 WB Image

WB analysis of purified CD4 recombinant protein using GTX13846 CD4 antibody [YTS177].
Lane 1 : 1 ug reduced purified mouse CD4 with histidine tag at C-terminus
Lane 2 : 0.5 ug reduced purified mouse CD4 with histidine tag at C-terminus
Dilution : 15 ug/ml

REFERENCE

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REVIEW

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Package List Price ($)
$ 399